C₅₃H₆₈O₁₅Si

Base Information

Chemical Name:C₅₃H₆₈O₁₅Si
CAS No.:256342-11-7
Molecular Formula:C₅₃H₆₈O₁₅Si
Molecular Weight:973.199
Hs Code.:

C<sub>53</sub>H<sub>68</sub>O<sub>15</sub>Si

Synonyms:C₅₃H₆₈O₁₅Si

Suppliers and Price of C₅₃H₆₈O₁₅Si

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₅₃H₆₈O₁₅Si

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₅₃H₆₈O₁₅Si

There total 40 articles about C₅₃H₆₈O₁₅Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 98-88-4
benzoyl chloride

: 256342-10-6
C₄₆H₆₄O₁₄Si

: 256342-11-7
C₅₃H₆₈O₁₅Si

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 ℃; for 25h;
DOI:10.1002/(SICI)1521-3773(19991115)38:22<3340::AID-ANIE3340>3.0.CO;2-2

Reference yield:

: 306726-10-3
(1R,2S,3S)-2,3-Bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-1-thiazol-2-yl-butan-1-ol

: 256342-11-7
C₅₃H₆₈O₁₅Si

Guidance literature:: Multi-step reaction with 22 steps

1.1: 98 percent / Et₃N; DMAP / CH₂Cl₂ / 2 h / 0 - 25 °C

2.1: molecular sieves 4 Angstroem / acetonitrile / 0.25 h / 25 °C

3.1: NaBH₄ / methanol / 0.5 h / 0 °C

3.2: H₂O; CuCl₂; CuO / acetonitrile / 2 h / 25 °C

4.1: 10.97 g / TBAF; AcOH / 2 h / 25 °C

5.1: 85 percent / DBU / CH₂Cl₂ / 0.5 h / 0 °C

6.1: nBu₂SnO / methanol / 3 h / Heating

6.2: TMSOTf / CH₂Cl₂ / 12 h / 0 - 25 °C

6.3: 10.82 g / PPTS; MeOH / 1 h / 25 °C

7.1: 87 percent / NaH / dimethylformamide / 1 h / 0 - 25 °C

8.1: 95 percent / NaOH; MeOH / diethyl ether / 1 h / 25 °C

9.1: NaH / dimethylformamide / 0.08 h / 0 °C

9.2: 90 percent / nBu₄NI / dimethylformamide / 4 h / 0 - 25 °C

10.1: 91 percent / DDQ; H₂O / CH₂Cl₂ / 1 h / 0 - 25 °C

11.1: 97 percent / 2,6-lutidine / CH₂Cl₂ / 1 h / 0 - 25 °C

12.1: DABCO / [(Ph₃P)3RhCl] / aq. ethanol / 2 h / Heating

13.1: 9.27 g / NMO; OsO₄; H₂O / acetone / 8 h / 25 °C

14.1: nBu₂SnO / toluene / 3 h / Heating

14.2: toluene / 1 h / 0 - 25 °C

15.1: 96 percent / Et₃N; DMAP / CH₂Cl₂ / 2 h / 0 - 25 °C

16.1: 96 percent / Et₃N; MeOH / CH₂Cl₂ / 6 h / 40 °C

17.1: 92 percent / SnCl₂; molecular sieves 4 Angstroem / diethyl ether / 3 h / 0 - 25 °C

18.1: 98 percent / K₂CO₃; MeOH / diethyl ether / 12 h / 25 °C

19.1: aq. NaIO₄; NaHCO₃ / methanol; CH₂Cl₂ / 2 h / 25 °C

20.1: 430 mg / iPr₂NH; vinyl acetate / toluene / 12 h / 140 °C

21.1: 95 percent / TBAF / tetrahydrofuran / 0.5 h / 0 °C

22.1: 97 percent / Et₃N; DMAP / CH₂Cl₂ / 2 h / 0 - 25 °C

With 1,4-diaza-bicyclo[2.2.2]octane; 2,6-dimethylpyridine; methanol; dmap; sodium hydroxide; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; vinyl acetate; N-methyl-2-indolinone; 4 A molecular sieve; tetrabutyl ammonium fluoride; water; sodium hydride; di(n-butyl)tin oxide; sodium hydrogencarbonate; potassium carbonate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; tin(ll) chloride; Wilkinson's catalyst; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone; toluene; acetonitrile; 1.1: Esterification / 2.1: Methylation / 3.1: Reduction / 3.2: Ring cleavage / 4.1: Cyclization / 5.1: Addition / 6.1: Cyclization / 6.2: Ring cleavage / 6.3: Methanolysis / 7.1: Methylation / 8.1: Debenzoylation / 9.1: Metallation / 9.2: Etherification / 10.1: Oxidation / 11.1: Etherification / 12.1: Isomerization / 13.1: Oxidation / 14.1: Cyclization / 14.2: Ring cleavage / 15.1: Esterification / 16.1: Deacylation / 17.1: Glycosidation / 18.1: Debenzoylation / 19.1: Oxidation / 20.1: Cyclizati;
DOI:10.1002/1521-3765(20000901)6:17<3116::AID-CHEM3116>3.0.CO;2-8

Reference yield:

: 306726-12-5
Benzoic acid (1R,2R,3S)-2,3-bis-allyloxy-4-(tert-butyl-diphenyl-silanyloxy)-1-thiazol-2-yl-butyl ester

: 256342-11-7
C₅₃H₆₈O₁₅Si

Guidance literature:: Multi-step reaction with 21 steps

1.1: molecular sieves 4 Angstroem / acetonitrile / 0.25 h / 25 °C

2.1: NaBH₄ / methanol / 0.5 h / 0 °C

2.2: H₂O; CuCl₂; CuO / acetonitrile / 2 h / 25 °C

3.1: 10.97 g / TBAF; AcOH / 2 h / 25 °C

4.1: 85 percent / DBU / CH₂Cl₂ / 0.5 h / 0 °C

5.1: nBu₂SnO / methanol / 3 h / Heating

5.2: TMSOTf / CH₂Cl₂ / 12 h / 0 - 25 °C

5.3: 10.82 g / PPTS; MeOH / 1 h / 25 °C

6.1: 87 percent / NaH / dimethylformamide / 1 h / 0 - 25 °C

7.1: 95 percent / NaOH; MeOH / diethyl ether / 1 h / 25 °C

8.1: NaH / dimethylformamide / 0.08 h / 0 °C

8.2: 90 percent / nBu₄NI / dimethylformamide / 4 h / 0 - 25 °C

9.1: 91 percent / DDQ; H₂O / CH₂Cl₂ / 1 h / 0 - 25 °C

10.1: 97 percent / 2,6-lutidine / CH₂Cl₂ / 1 h / 0 - 25 °C

11.1: DABCO / [(Ph₃P)3RhCl] / aq. ethanol / 2 h / Heating

12.1: 9.27 g / NMO; OsO₄; H₂O / acetone / 8 h / 25 °C

13.1: nBu₂SnO / toluene / 3 h / Heating

13.2: toluene / 1 h / 0 - 25 °C

14.1: 96 percent / Et₃N; DMAP / CH₂Cl₂ / 2 h / 0 - 25 °C

15.1: 96 percent / Et₃N; MeOH / CH₂Cl₂ / 6 h / 40 °C

16.1: 92 percent / SnCl₂; molecular sieves 4 Angstroem / diethyl ether / 3 h / 0 - 25 °C

17.1: 98 percent / K₂CO₃; MeOH / diethyl ether / 12 h / 25 °C

18.1: aq. NaIO₄; NaHCO₃ / methanol; CH₂Cl₂ / 2 h / 25 °C

19.1: 430 mg / iPr₂NH; vinyl acetate / toluene / 12 h / 140 °C

20.1: 95 percent / TBAF / tetrahydrofuran / 0.5 h / 0 °C

21.1: 97 percent / Et₃N; DMAP / CH₂Cl₂ / 2 h / 0 - 25 °C

With 1,4-diaza-bicyclo[2.2.2]octane; 2,6-dimethylpyridine; methanol; dmap; sodium hydroxide; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; vinyl acetate; N-methyl-2-indolinone; 4 A molecular sieve; tetrabutyl ammonium fluoride; water; sodium hydride; di(n-butyl)tin oxide; sodium hydrogencarbonate; potassium carbonate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; tin(ll) chloride; Wilkinson's catalyst; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone; toluene; acetonitrile; 1.1: Methylation / 2.1: Reduction / 2.2: Ring cleavage / 3.1: Cyclization / 4.1: Addition / 5.1: Cyclization / 5.2: Ring cleavage / 5.3: Methanolysis / 6.1: Methylation / 7.1: Debenzoylation / 8.1: Metallation / 8.2: Etherification / 9.1: Oxidation / 10.1: Etherification / 11.1: Isomerization / 12.1: Oxidation / 13.1: Cyclization / 13.2: Ring cleavage / 14.1: Esterification / 15.1: Deacylation / 16.1: Glycosidation / 17.1: Debenzoylation / 18.1: Oxidation / 19.1: Cyclization / 20.1: Silyl ether;
DOI:10.1002/1521-3765(20000901)6:17<3116::AID-CHEM3116>3.0.CO;2-8