Docosahexaenoyl Ethanolamide

Base Information

Chemical Name:Docosahexaenoyl Ethanolamide
CAS No.:162758-94-3
Molecular Formula:C24H37 N O2
Molecular Weight:371.563
Hs Code.:
DSSTox Substance ID:DTXSID50678596
Wikidata:Q27158436
Metabolomics Workbench ID:4656
ChEMBL ID:CHEMBL1482206
Mol file:162758-94-3.mol

Synonyms:N-docosahexaenoylethanolamine;synaptamide

Suppliers and Price of Docosahexaenoyl Ethanolamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Docosahexaenoyl ethanolamide ≥98% (HPLC)
5mg
$ 80.50

Sigma-Aldrich
Docosahexaenoyl ethanolamide ≥98% (HPLC)
25mg
$ 311.00

Medical Isotopes, Inc.
Synaptamide
250 mg
$ 2200.00

Medical Isotopes, Inc.
Synaptamide
25 mg
$ 650.00

DC Chemicals
Synaptamide >98%
50 mg
$ 225.00

DC Chemicals
Synaptamide >98%
10 mg
$ 76.00

CSNpharm
Synaptamide
5mg
$ 50.00

Crysdot
Synaptamide 98+%
5mg
$ 42.00

Crysdot
Synaptamide 98+%
10mg
$ 59.00

Cayman Chemical
Docosahexaenoyl Ethanolamide ≥98%
50mg
$ 264.00

Total 8 raw suppliers

Chemical Property of Docosahexaenoyl Ethanolamide

Chemical Property:

PSA：49.33000
LogP:5.96370
Storage Temp.:?20°C
Solubility.:Soluble in DMSO (up to 35 mg/ml)
XLogP3:5.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:16
Exact Mass:371.282429423
Heavy Atom Count:27
Complexity:511

Purity/Quality:

97% ^*data from raw suppliers

Docosahexaenoyl ethanolamide ≥98% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC=CCC=CCC=CCC=CCC=CCC=CCCC(=O)NCCO
Isomeric SMILES:CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCO
Description Synaptamide (162758-94-3) is an anandamide-like lipid mediator produced from DHA in the brain. Stimulates neurite growth, synaptogenesis and glutamatergic synaptic activity in developing hippocampal neurons at 10-100 nM.1?Potently induces neuronal differentiation of neural stem cells.2?Promotes growth of cortical axons via modulation of hedgehog signaling.3?Binds to and activates orphan receptor GPR110, stimulating cAMP production at low nM concentrations.4?Reduces LPS-induced TNFα production in cultured microglia cells and ameliorates LPS-induced neuroinflammation in a mouse model.5

Technology Process of Docosahexaenoyl Ethanolamide

There total 1 articles about Docosahexaenoyl Ethanolamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 81926-94-5,84494-72-4
all-(Z)-ethyl 4,7,10,13,16,19-docosahexaenoate

: 141-43-5
ethanolamine

: 6217-54-5
docosahexaenoic acid

: 162758-94-3
N-docosahexaenoylethanolamine

Guidance literature:: With Novozym 435 lipase on resin; In acetone; at 35 ℃; for 8h; Green chemistry; Enzymatic reaction;
DOI:10.1016/j.bmcl.2014.10.084

Reference yield:

: 162758-94-3
N-docosahexaenoylethanolamine

: C₂₄H₃₇NO₃

: C₂₄H₃₇NO₃

Guidance literature:: With tert.-butylhydroperoxide; peroxygenase from oat flour; In aq. phosphate buffer; acetone; at 25 ℃; for 4h; pH=7.4; Reagent/catalyst; Solvent; Concentration; Overall yield = 44 mg; stereoselective reaction; Catalytic behavior; Enzymatic reaction;
DOI:10.1016/j.bioorg.2021.105014