Raxatrigine hydrochloride

Base Information

Chemical Name:Raxatrigine hydrochloride
CAS No.:934240-31-0
Molecular Formula:C₁₈H₁₉FN₂O₂*ClH
Molecular Weight:350.82
Hs Code.:
European Community (EC) Number:827-335-2
UNII:7L3OLR4M8T
ChEMBL ID:CHEMBL3544912
NCI Thesaurus Code:C152900
Wikidata:Q27268497
Mol file:934240-31-0.mol

Synonyms:Raxatrigine hydrochloride;934240-31-0;Raxatrigine HCl;(2S,5R)-5-(4-((2-Fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide hydrochloride;GSK-1014802 hydrochloride;CNV1014802 hydrochloride;Vixotrigine hydrochloride;CNV1014802 (hydrochloride);7L3OLR4M8T;934240-31-0 (HCl);CNV1014802A;GSK1014802A;CNV-1014802A;GSK-1014802A;1044910-30-6;Vixotrigine hydrochloride (USAN);VIXOTRIGINE HYDROCHLORIDE [USAN];2-Pyrrolidinecarboxamide, 5-[4-[(2-fluorophenyl)methoxy]phenyl]-, hydrochloride (1:1), (2S,5R)-;CNV-1014802 hydrochloride;UNII-7L3OLR4M8T;Raxatrigine hydrochloride [USAN];2-PYRROLIDINECARBOXAMIDE, 5-(4-((2-FLUOROPHENYL)METHOXY)PHENYL)-, HYDROCHLORIDE (1:1), (2S,5R)-;GSK2 HCl;C18H20ClFN2O2;SCHEMBL312349;CNV 1014802 hydrochloride;BIIB-074 HYDROCHLORIDE;CHEMBL3544912;GSK 1014802 HCl;BIIB 074 HCl,Vixotrigine HCl;(2S,5R)-5-{4-[(2-fluorophenyl)methoxy]phenyl}pyrrolidine-2-carboxamide hydrochloride;HEPUBAGOKRIZEO-PPPUBMIESA-N;GSK1014802 HYDROCHLORIDE;HY-12796A;MFCD28900694;AKOS025395749;Vixotrigine HCl;CNV1014802 HCl;AS-49442;VIXOTRIGINE HYDROCHLORIDE [WHO-DD];D11180;I10406;GSK1014802;CNV-1014802 HCl;A922707;Q27268497;(5R)-5-(4-[2-fluorobenzyloxy]phenyl)-L-prolinamide hydrochloride;(5R)-5-(4-{[(2-Fluorophenyl)methyl]oxyphenyl)-L-prolinamide-HCl;cis-5-(4-((2-Fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamidehydrochloride;(2S,5R)-5-(4-(2-fluorobenzyloxy)phenyl)pyrrolidine-2-carboxamide hydrochloride;(2s,5r)-5-[4-[(2-fluorophenyl)methoxy]phenyl]-2-pyrrolidinecarboxamide hcl;(2S,5R)-5-[4-[(2-fluorophenyl)methoxy]phenyl]pyrrolidine-2-carboxamide;hydrochloride;cis-5-(4-((2-Fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide hydrochloride

Suppliers and Price of Raxatrigine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
RaxatrigineHydrochloride
100mg
$ 1280.00

DC Chemicals
Raxatriginehydrochloride >98%,ee>98%
100 mg
$ 550.00

DC Chemicals
Raxatriginehydrochloride >98%,ee>98%
1 g
$ 2100.00

DC Chemicals
Raxatriginehydrochloride >98%,ee>98%
250 mg
$ 1000.00

Crysdot
CNV1014802hydrochloride 97+%
50mg
$ 871.00

Crysdot
CNV1014802hydrochloride 97+%
25mg
$ 484.00

Crysdot
CNV1014802hydrochloride 97+%
10mg
$ 256.00

ChemScene
Raxatriginehydrochloride 99.17%
5mg
$ 180.00

ChemScene
Raxatriginehydrochloride 99.17%
50mg
$ 1020.00

ChemScene
Raxatriginehydrochloride 99.17%
10mg
$ 288.00

Total 15 raw suppliers

Chemical Property of Raxatrigine hydrochloride

Chemical Property:

Melting Point:>206°C (dec.)
Storage Temp.:Hygroscopic, Refrigerator, under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly, Sonicated)
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:350.1197337
Heavy Atom Count:24
Complexity:399

Purity/Quality:

97% ^*data from raw suppliers

RaxatrigineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(NC1C2=CC=C(C=C2)OCC3=CC=CC=C3F)C(=O)N.Cl
Isomeric SMILES:C1C[C@H](N[C@H]1C2=CC=C(C=C2)OCC3=CC=CC=C3F)C(=O)N.Cl
Recent EU Clinical Trials:A Phase 2 Placebo-Controlled, Double-Blind, Enriched Enrollment Randomized Withdrawal Study to Evaluate the Efficacy and Safety of BIIB074 (Vixotrigine) in Treating Pain Experienced by Subjects With Confirmed Small Fibre Neuropathy That Is Idiopathic or Associated With Diabetes Mellitus
Uses Raxatrigine Hydrochloride is used as co-therapy for the treatment of epilepsy and related disorders.

Technology Process of Raxatrigine hydrochloride

There total 27 articles about Raxatrigine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%