2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethanamine

Base Information

Chemical Name:2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethanamine
CAS No.:448964-37-2
Molecular Formula:C13H17NO
Molecular Weight:203.284
Hs Code.:2932999099
DSSTox Substance ID:DTXSID00433394
Nikkaji Number:J3.085.852B
Mol file:448964-37-2.mol

Synonyms:448964-37-2;2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethanamine;2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-ylethylamine;2-(2,6,7,8-tetrahydro-1H-cyclopenta[e][1]benzofuran-8-yl)ethanamine;2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-amine;rac Despropionyl Ramelteon;SCHEMBL340076;Discontinued see: D297275;SCHEMBL11917773;1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-ethanamine;DTXSID00433394;BFNUHWYOQCGTCA-UHFFFAOYSA-N;Discontinued see: D297275"";BCP12291;CS-M1901;SB67398;CS-14199;FT-0666269;FT-0774273;2-(1,6,7,8,-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine;2-(1,6,7,8-tetrahydro-2H-indeno [5,4-b] furan-8-yl)ethylamine

Suppliers and Price of 2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethanamine 95+%
1g
$ 377.00

American Custom Chemicals Corporation
2,6,7,8-TETRAHYDRO-1H-INDENO[5,4-B]FURAN-8-YLETHYLAMINE 95.00%
10MG
$ 1612.96

American Custom Chemicals Corporation
2,6,7,8-TETRAHYDRO-1H-INDENO[5,4-B]FURAN-8-YLETHYLAMINE 95.00%
1MG
$ 679.14

Total 38 raw suppliers

Chemical Property of 2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethanamine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.587
Boiling Point:317.2 °C at 760 mmHg
PKA:10.27±0.10(Predicted)
Flash Point:127.9 °C
PSA：21.26000
Density:1.12g/cm³
LogP:2.60920
Storage Temp.:2-8°C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:203.131014166
Heavy Atom Count:15
Complexity:231

Purity/Quality:

97% ^*data from raw suppliers

2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethanamine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C1CCN)C3=C(C=C2)OCC3
Uses A tricyclic indan derivative; as potential therapeutic agent for sleep disorders Ramelteon (R110050) intermediate.

Technology Process of 2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethanamine

There total 20 articles about 2-(2,6,7,8-Tetrahydro-1H-indeno[5,4-b]furan-8-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: N-tert-butoxycarbonyl-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylethylamine

: 448964-37-2,196597-81-6
2?(1,6,7,8?tetrahydro?2H?indeno[5,4?b]furan?8?yl)?1?ethylamine

Guidance literature:: With methanol; methanesulfonic acid; calcium chloride; at 25 ℃; for 5h; Concentration; Reagent/catalyst; Temperature;

Reference yield: 81.0%

: 196597-79-2
(E)-2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile

: 448964-37-2,196597-81-6
2?(1,6,7,8?tetrahydro?2H?indeno[5,4?b]furan?8?yl)?1?ethylamine

Guidance literature:: With ammonia; hydrogen; nickel; at 40 ℃; under 3600.36 Torr;
DOI:10.1021/jm0201159

Reference yield:

: 1053239-39-6
2?(1,6,7,8?tetrahydro?2H?indeno[5,4?b]furan?8?yl)ethylamine hydrochloride

: 448964-37-2,196597-81-6
2?(1,6,7,8?tetrahydro?2H?indeno[5,4?b]furan?8?yl)?1?ethylamine

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 60 ℃; for 1h; under 750.075 Torr; Pressure; Temperature; Large scale;