{(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone

Base Information

Chemical Name:{(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone
CAS No.:1316794-53-2
Molecular Formula:C₂₂H₃₄O₅Si
Molecular Weight:406.594
Hs Code.:

Synonyms:{(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone

Suppliers and Price of {(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone

There total 6 articles about {(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1224587-86-3
(4R,5R)-4-benzoyl-2,2-dimethyl-5-vinyl-1,3-dioxolane

: 1316794-59-8
(6R,9R,E)-2,2,3,3,12,12,13,13-octamethyl-4,11-dioxa-3,12-disilatetradec-7-ene-6,9-diol

: 1316794-53-2
{(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone

Guidance literature:: With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 50 ℃; for 3h;
DOI:10.1039/c1cc11805f

Reference yield:

: 124150-87-4
tert-butyldimethylsilyl (R)-glycidyl ether

: 1316794-53-2
{(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone

Guidance literature:: Multi-step reaction with 3 steps

1: n-butyllithium / tetrahydrofuran; hexane / -10 - 20 °C

2: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 1.5 h / 50 °C

3: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 3 h / 50 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; n-butyllithium; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1039/c1cc11805f

Reference yield:

: 119125-28-9,136917-96-9,136984-28-6
(R)-1-(tert-butyldimethylsilyloxy)but-3-en-2-ol

: 1316794-53-2
{(4R,5R)-5-[(S,E)-4-(tert-butyldimethylsilyloxy)-3-hydroxybut-1-enyl]-2,2-dimethyl-1,3-dioxolan-4-yl}phenylmethanone

Guidance literature:: Multi-step reaction with 2 steps

1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 1.5 h / 50 °C

2: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 3 h / 50 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane;
DOI:10.1039/c1cc11805f