15N-N-benzylaniline

Base Information

• Chemical Name: 15N-N-benzylaniline
• CAS No.: 1049739-83-4
• Molecular Formula: C₁₃H₁₃N
• Molecular Weight: 184.246
• Mol file: 1049739-83-4.mol

Synonyms:15N-N-benzylaniline

Chemical Property of 15N-N-benzylaniline

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 15N-N-benzylaniline

There total 4 articles about 15N-N-benzylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(15N)-aniline (7022-92-6) + dibenzylamine (103-49-1) → 15N-N-benzylaniline (1049739-83-4)

Guidance literature:

With 1-hydroxytetraphenylcyclopentadienyl(tetraphenyl-2,4-cyclopentadien-1-one)-μ-hydrotetracarbonyldiruthenium(II); In tert-Amyl alcohol; at 150 ℃; for 24h; Inert atmosphere;

DOI:10.1039/b803114b

Reference yield: 91.0%

C13H12N(15)N + benzyl alcohol (100-51-6,185532-71-2) → 15N-N-benzylaniline (1049739-83-4) + benzamide (55-21-0,27208-38-4)

Guidance literature:

With potassium tert-butylate; In toluene; at 120 ℃; for 15h; Reagent/catalyst; Schlenk technique; Glovebox; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.0c00281

Reference yield:

(15N)-aniline (7022-92-6) + benzyl alcohol (100-51-6,185532-71-2) → 15N-N-benzylaniline (1049739-83-4)

Guidance literature:

With potassium tert-butylate; In 1,4-dioxane; at 120 ℃; for 15h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1039/d0cc04831c

upstream raw materials:

(15N)-aniline

dibenzylamine

benzonitrile

benzyl alcohol

Refernces

• 1、 Hu, Mao-Lin,Jia, Xiaofei,Liang, Zuyu,Lu, Fenghong,Zhang, Chunyan,Zhang, Guoying. "Base-mediated cascade amidination/: N -alkylation of amines by alcohols". supporting information. p. 10489 - 10492. Retrieved 2020/10/02.