4,5-dibromopentanoic acid

Base Information

• Chemical Name: 4,5-dibromopentanoic acid
• CAS No.: 78181-02-9
• Molecular Formula: C₅H₈Br₂O₂
• Molecular Weight: 259.925
• Mol file: 78181-02-9.mol

Synonyms:4,5-dibromopentanoic acid

Chemical Property of 4,5-dibromopentanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,5-dibromopentanoic acid

There total 2 articles about 4,5-dibromopentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

4-pentenoic acid sodium salt → 5-bromomethyl-γ-butyrolactone (32730-32-8) + 4,5-dibromopentanoic acid (78181-02-9)

Guidance literature:

With dihydrogen peroxide; sodium bromide; 1-[4-N,N-bis(carboxylatomethyl)aminophenyltelluro]-3-phenoxypropane disodium salt; In water; at 20 ℃; for 24h; pH=6;

DOI:10.1021/ol0068142

Reference yield: 28.0%

pent-4-enoic acid (591-80-0) → 5-bromomethyl-γ-butyrolactone (32730-32-8) + 4,5-dibromopentanoic acid (78181-02-9)

Guidance literature:

With bromine; for 0.25h; Phase-vanishing reaction with phase screen; Neat (no solvent);

DOI:10.3762/bjoc.5.75

Reference yield: 69.0%

4,5-dibromopentanoic acid (78181-02-9) → 4-pentynoic acid (6089-09-4)

Guidance literature:

With sodium amide; In diethyl ether; ammonia; at -33 ℃; for 1.5h;

DOI:10.1023/A:1011303024847

upstream raw materials:

pent-4-enoic acid

Downstream raw materials:

4-pentynoic acid

pent-4-enoic acid

pent-3-ynoic acid

5-bromopent-4(Z)-enoic acid