4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine

Base Information

• Chemical Name: 4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine
• CAS No.: 102408-83-3
• Molecular Formula: C₂₄H₂₁NO₄
• Molecular Weight: 387.435

Synonyms:4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine

Chemical Property of 4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine

There total 4 articles about 4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

1-phenyl-7,8,9,10-tetrahydrocycloheptaindolizine (102428-79-5) + dimethyl acetylenedicarboxylate (762-42-5) → 4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine (102408-83-3)

Guidance literature:

palladium on activated charcoal; In xylene; for 50h; Heating; other solvent (toluene);

DOI:10.1002/jhet.5570220425

Reference yield:

2,3-cycloheptenopyridine (7197-96-8) → 4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine (102408-83-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / acetone / 1) 2 h, reflux; 2) room temp., overnight

2: 74 percent / NaHCO₃ / ethanol / Heating; overnight

3: 61 percent / Pd/C / xylene / 50 h / Heating; other solvent (toluene)

With sodium hydrogencarbonate; palladium on activated charcoal; In ethanol; acetone; xylene;

DOI:10.1002/jhet.5570220425

Reference yield:

N-phenacyl-2,3-cycloheptenopyridinium bromide (102408-78-6) → 4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine (102408-83-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / NaHCO₃ / ethanol / Heating; overnight

2: 61 percent / Pd/C / xylene / 50 h / Heating; other solvent (toluene)

With sodium hydrogencarbonate; palladium on activated charcoal; In ethanol; xylene;

DOI:10.1002/jhet.5570220425

upstream raw materials:

1-phenyl-7,8,9,10-tetrahydrocycloheptaindolizine

dimethyl acetylenedicarboxylate

2,3-cycloheptenopyridine

N-phenacyl-2,3-cycloheptenopyridinium bromide

Downstream raw materials:

C₂₄H₁₉NO₄

C₂₄H₁₈BrNO₄

C₂₄H₁₇NO₄

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 102408-83-3 4,5,6,7-tetrahydro-1,2-bis(methoxycarbonyl)-3-phenylcycloheptapyrrolo-<2,1,5-cd>indolizine

Send

Send

Metric Ton KG G Pound L ML

Send

Send