C₃₂H₄₄O₇S

Base Information

• Chemical Name: C₃₂H₄₄O₇S
• CAS No.: 1442422-47-0
• Molecular Formula: C₃₂H₄₄O₇S
• Molecular Weight: 572.763
• Mol file: 1442422-47-0.mol

Synonyms:C₃₂H₄₄O₇S

Chemical Property of C₃₂H₄₄O₇S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₂H₄₄O₇S

There total 7 articles about C₃₂H₄₄O₇S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C30H40O7S + vinyl magnesium bromide (1826-67-1) → C32H44O7S (1442422-48-1) + C32H44O7S (1442422-47-0)

Guidance literature:

In tetrahydrofuran; at -78 ℃; for 2h; Overall yield = 6.5 g; Inert atmosphere;

DOI:10.1016/j.tet.2013.04.094

Reference yield:

2-methyl-5-tert-butylthiophenol (7340-90-1) → C32H44O7S (1442422-48-1) + C32H44O7S (1442422-47-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: boron trifluoride diethyl etherate / dichloromethane / -78 - 20 °C / Inert atmosphere

2.1: sodium methylate / methanol / 20 °C / Inert atmosphere

3.1: camphor-10-sulfonic acid / methanol / 8 h / Reflux; Inert atmosphere

4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 26 h / -40 - -5 °C / Inert atmosphere

5.1: oxalyl dichloride; dimethyl sulfoxide / tetrahydrofuran / 5 h / -60 - -4 °C / Inert atmosphere

5.2: 2 h / -40 - 20 °C / Inert atmosphere

6.1: tetrahydrofuran / 2 h / -78 °C / Inert atmosphere

With oxalyl dichloride; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; sodium methylate; sodium hydride; dimethyl sulfoxide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; mineral oil; 5.1: |Swern Oxidation;

DOI:10.1016/j.tet.2013.04.094

Reference yield:

(2-methyl-5-tert-butylphenyl) 2,3,4,6-tetra-O-acetyl-1-thia-α-D-mannopyranoside (1379519-57-9) → C32H44O7S (1442422-48-1) + C32H44O7S (1442422-47-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium methylate / methanol / 20 °C / Inert atmosphere

2.1: camphor-10-sulfonic acid / methanol / 8 h / Reflux; Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 26 h / -40 - -5 °C / Inert atmosphere

4.1: oxalyl dichloride; dimethyl sulfoxide / tetrahydrofuran / 5 h / -60 - -4 °C / Inert atmosphere

4.2: 2 h / -40 - 20 °C / Inert atmosphere

5.1: tetrahydrofuran / 2 h / -78 °C / Inert atmosphere

With oxalyl dichloride; camphor-10-sulfonic acid; sodium methylate; sodium hydride; dimethyl sulfoxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; mineral oil; 4.1: |Swern Oxidation;

DOI:10.1016/j.tet.2013.04.094

upstream raw materials:

(2-methyl-5-tert-butylphenyl) 2,3,4,6-tetra-O-acetyl-1-thia-α-D-mannopyranoside

(2-methyl-5-tert-butylphenyl) 1-thio-α-D-mannopyranoside

(2-methyl-5-tert-butylphenyl) 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-1-thia-α-D-mannopyranoside

vinyl magnesium bromide

Refernces