toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester

Base Information

Chemical Name:toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester
CAS No.:214786-32-0
Molecular Formula:C₁₆H₂₄O₆S
Molecular Weight:344.429
Hs Code.:

Synonyms:toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester

Suppliers and Price of toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester

There total 11 articles about toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 173239-11-7
(3R,4R)-3,4-isopropylidenehexane-1,6-diol

: 98-59-9
p-toluenesulfonyl chloride

: 214786-32-0
toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 ℃;
DOI:10.1016/j.tet.2004.02.065

Reference yield:

: 29311-53-3
(E)-3-hexene-1,6-dioic acid

: 214786-32-0
toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / acetyl chloride / Heating

2: 64 percent / AD-mix-β; methanesulfonamide; NaHCO3 / H2O; 2-methyl-propan-2-ol / 0 °C

3: 9.8 g / TsOH*H₂O; molecular sieves

4: lithium aluminum hydride / tetrahydrofuran / Heating

5: 50 percent / DMAP; Et₃N / CH₂Cl₂ / 0 °C

With dmap; lithium aluminium tetrahydride; molecular sieve; methanesulfonamide; AD-mix-β; sodium hydrogencarbonate; toluene-4-sulfonic acid; triethylamine; acetyl chloride; In tetrahydrofuran; dichloromethane; water; tert-butyl alcohol; 2: Sharpless asymmetric dihydroxylation;
DOI:10.1016/j.tet.2004.02.065

Reference yield:

: 90157-48-5
diisopropyl (E)-hex-3-enedioate

: 214786-32-0
toluene-4-sulfonic acid 2-[5-(2-hydroxyethyl)-2,2-dimethyl-[1,3]-dioxolan-4-yl] ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 64 percent / AD-mix-β; methanesulfonamide; NaHCO3 / H2O; 2-methyl-propan-2-ol / 0 °C

2: 9.8 g / TsOH*H₂O; molecular sieves

3: lithium aluminum hydride / tetrahydrofuran / Heating

4: 50 percent / DMAP; Et₃N / CH₂Cl₂ / 0 °C

With dmap; lithium aluminium tetrahydride; molecular sieve; methanesulfonamide; AD-mix-β; sodium hydrogencarbonate; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; dichloromethane; water; tert-butyl alcohol; 1: Sharpless asymmetric dihydroxylation;
DOI:10.1016/j.tet.2004.02.065