2-AMINO-N-TERT-BUTYLBENZAMIDE

Base Information

• Chemical Name: 2-AMINO-N-TERT-BUTYLBENZAMIDE
• CAS No.: 1203-89-0
• Molecular Formula: C11H16N2O
• Molecular Weight: 192.261
• Hs Code.: 2924299090
• Mol file: 1203-89-0.mol

Synonyms:Benzamide,o-amino-N-tert-butyl- (7CI,8CI);2-Amino-N-tert-butylbenzamide;o-Aminobenzoyl-tert-butylamine;

Chemical Property of 2-AMINO-N-TERT-BUTYLBENZAMIDE

Chemical Property:

• Vapor Pressure: 2.36E-05mmHg at 25°C
• Melting Point: 124-125 °C
• Refractive Index: 1.551
• Boiling Point: 359.6 °C at 760 mmHg
• PKA: 14.72±0.46(Predicted)
• Flash Point: 171.3 °C
• PSA: 55.12000
• Density: 1.058 g/cm³
• LogP: 2.76920
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-N-tert-butylbenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-N-TERT-BUTYLBENZAMIDE

There total 8 articles about 2-AMINO-N-TERT-BUTYLBENZAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 2-amino-N-(1,1-dimethylethyl)benzamide (1203-89-0)

Guidance literature:

Reference yield: 73.0%

isatoic anhydride (118-48-9) + tert-butylamine (75-64-9) → 2-amino-N-(1,1-dimethylethyl)benzamide (1203-89-0)

Guidance literature:

dmap; In N,N-dimethyl-formamide; for 6h; Ambient temperature;

DOI:10.1055/s-1982-29772

Reference yield: 71.0%

2-aminobenzoic acid 2,5-dioxopyrrolidin-1-yl ester (55668-30-9) + tert-butylamine (75-64-9) → 2-amino-N-(1,1-dimethylethyl)benzamide (1203-89-0)

Guidance literature:

for 1h; Heating;

DOI:10.1055/s-1980-29185

upstream raw materials:

isatoic anhydride

tert-butylamine

2-aminobenzoic acid 2,5-dioxopyrrolidin-1-yl ester

anthranilic acid

Downstream raw materials:

[(1S,2S)-1-Benzyl-3-(2-tert-butylcarbamoyl-phenylamino)-2-hydroxy-propyl]-carbamic acid tert-butyl ester

[(1S,2R)-1-Benzyl-3-(2-tert-butylcarbamoyl-phenylamino)-2-hydroxy-propyl]-carbamic acid tert-butyl ester

N-tert-butyl-N′-(methoxycarbonyl)-2-aminobenzamide

1-(4-methoxybenzyl)-1,2,3,4-tetrhydroquinazoline-2,4-dione