t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester

Base Information

• Chemical Name: t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester
• CAS No.: 174757-64-3
• Molecular Formula: C₃₂H₅₀N₂O₉
• Molecular Weight: 606.757

Synonyms:t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester

Chemical Property of t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester

There total 3 articles about t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleric acid (174833-92-2) + L-valyl-L-α-hydroxyisovaleric acid benzyl ester hydrochloride → t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester (174757-64-3)

Guidance literature:

With 4-methyl-morpholine; dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 9h; Ambient temperature;

DOI:10.1016/0040-4020(95)00962-0

Reference yield:

t-Boc-L-valine (13734-41-3) → t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester (174757-64-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / dimethylaminopyridine, DCC / CH₂Cl₂ / 4 h / Ambient temperature

2: 90 percent / H₂ / 10percent Pd/C / methanol / 20 h / Ambient temperature

3: 100 percent / DCC, dimethylaminopyridine, N-methylmorpholine / CH₂Cl₂ / 9 h / Ambient temperature

With 4-methyl-morpholine; dmap; hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; dichloromethane;

DOI:10.1016/0040-4020(95)00962-0

Reference yield:

t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester (174833-91-1) → t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester (174757-64-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / H₂ / 10percent Pd/C / methanol / 20 h / Ambient temperature

2: 100 percent / DCC, dimethylaminopyridine, N-methylmorpholine / CH₂Cl₂ / 9 h / Ambient temperature

With 4-methyl-morpholine; dmap; hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; dichloromethane;

DOI:10.1016/0040-4020(95)00962-0

upstream raw materials:

t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleric acid

t-Boc-L-valine

t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 174757-64-3 t-butoxycarbonyl-L-valyl-L-α-hydroxyisovaleryl-L-valyl-L-α-hydroxyisovaleric acid benzyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send