7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin

Base Information

• Chemical Name: 7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin
• CAS No.: 865541-43-1
• Molecular Formula: C₂₁H₂₈O₃SSi
• Molecular Weight: 388.603
• Mol file: 865541-43-1.mol

Synonyms:7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin

Chemical Property of 7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin

There total 3 articles about 7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → 7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin (865541-43-1)

Guidance literature:

Multi-step reaction with 3 steps

1: imidazole / dimethylformamide

2: CHCl₃ / 20 °C

3: 63 percent / Et₃N / CHCl₃ / 60 °C

With 1H-imidazole; triethylamine; In chloroform; N,N-dimethyl-formamide; 3: hetero Diels-Alder reaction;

DOI:10.1039/b507496g

Reference yield:

3-((tert-butyldimethylsilyl)oxy)phenol (161006-18-4) → 7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin (865541-43-1)

Guidance literature:

Multi-step reaction with 2 steps

1: CHCl₃ / 20 °C

2: 63 percent / Et₃N / CHCl₃ / 60 °C

With triethylamine; In chloroform; 2: hetero Diels-Alder reaction;

DOI:10.1039/b507496g

Reference yield:

recorcinol (108-46-3) → 7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin (865541-43-1)

Guidance literature:

Multi-step reaction with 3 steps

1: imidazole / dimethylformamide

2: CHCl₃ / 20 °C

3: 63 percent / Et₃N / CHCl₃ / 60 °C

With 1H-imidazole; triethylamine; In chloroform; N,N-dimethyl-formamide; 3: hetero Diels-Alder reaction;

DOI:10.1039/b507496g

upstream raw materials:

tert-butyldimethylsilyl chloride

3-((tert-butyldimethylsilyl)oxy)phenol

recorcinol

Downstream raw materials:

7-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydro-2-(4-methoxy-phenyl)-1,4-benzoxathiin 4,4-dioxide