1,3-di(p-methoxybenzyl)-2-N-phenylthiocarbamoylimidazolinium inner salt

Base Information

• Chemical Name: 1,3-di(p-methoxybenzyl)-2-N-phenylthiocarbamoylimidazolinium inner salt
• CAS No.: 885722-12-3
• Molecular Formula: C₂₆H₂₇N₃O₂S
• Molecular Weight: 445.585
• Mol file: 885722-12-3.mol

Synonyms:1,3-di(p-methoxybenzyl)-2-N-phenylthiocarbamoylimidazolinium inner salt

Chemical Property of 1,3-di(p-methoxybenzyl)-2-N-phenylthiocarbamoylimidazolinium inner salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-di(p-methoxybenzyl)-2-N-phenylthiocarbamoylimidazolinium inner salt

There total 2 articles about 1,3-di(p-methoxybenzyl)-2-N-phenylthiocarbamoylimidazolinium inner salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

C19H23N2O2(1+)*Cl(1-) + phenyl isothiocyanate (103-72-0) → 1,3-di(p-methoxybenzyl)-2-N-phenylthiocarbamoylimidazolinium inner salt (885722-12-3)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 10 - 20 ℃;

DOI:10.1039/b517700f

Reference yield:

1,3-bis-(4-methoxy-benzyl)-4,5-dihydro-3H-imidazol-1-ium + phenyl isothiocyanate (103-72-0) → 1,3-di(p-methoxybenzyl)-2-N-phenylthiocarbamoylimidazolinium inner salt (885722-12-3)

Guidance literature:

With sodium hydride;

DOI:10.1021/jo802687m

Reference yield: 93.0%

1,3-di(p-methoxybenzyl)-2-N-phenylthiocarbamoylimidazolinium inner salt (885722-12-3) + dimethyl acetylenedicarboxylate (762-42-5) → dimethyl 1,3-di-(p-methoxybenzyl)-2'-phenylimino-2',3'-dihydrospiro[imidazoline-2,3'-thiophene]-4',5'-dicarboxylate (885722-27-0) + dimethyl 1,3-di-(p-methoxybenzyl)-1'-phenyl-2',3'-dihydrospiro[imidazoline-2,3'-pyrrole]-2'-thione-4',5'-dicarboxylate

Guidance literature:

In 1,2-dichloro-ethane; at 20 - 30 ℃; for 0.5h;

DOI:10.1039/b517700f

upstream raw materials:

phenyl isothiocyanate

Downstream raw materials:

ethyl 1,3-di(para-methoxy)benzyl-1'-phenyl-2',3'-dihydrospiro(imidazolidine-2,3'-pyrrole)-2'-thione-4'-carboxylate

dimethyl 1,3-di-(p-methoxybenzyl)-2'-phenylimino-2',3'-dihydrospiro[imidazoline-2,3'-thiophene]-4',5'-dicarboxylate

(E)-methyl 1,3-bis(4-methoxybenzyl)-1'-phenyl-5'-(2-phenylethylidene)-2'-thioxospiro[imidazolidine-2,3'-pyrrolidine]-4'-carboxylate

(2' Z,5'E)-methyl 4',5'-dihydro-1,3-bis(4-methoxybenzyl)-5'-(2-phenylethylidene)-2'-(phenylimino)spiro[imidazolidine-2,3'(2'H)-thiophene]-4'-carboxylate