Chemical Property of 2-(4-((4-Methoxybenzyl)oxy)phenyl)acetonitrile
Chemical Property:
- Vapor Pressure:2.05E-07mmHg at 25°C
- Melting Point:140℃
- Boiling Point:424.5°Cat760mmHg
- Flash Point:154.8°C
- PSA：42.25000
- Density:1.129g/cm3
- LogP:3.34028
- Storage Temp.:Sealed in dry,Room Temperature
- XLogP3:3
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:5
- Exact Mass:253.110278721
- Heavy Atom Count:19
- Complexity:293
- Purity/Quality:
-
99%, *data from raw suppliers
O4I1 *data from reagent suppliers
Safty Information:
- Pictogram(s):
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.;
- Hazard Codes:
Xn:Harmful;
- Statements:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.;
- Safety Statements:
S36/37:Wear suitable protective clothing and gloves.;
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:COC1=CC=C(C=C1)COC2=CC=C(C=C2)CC#N
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Description
O4I1 is an inducer of Oct3/4 expression and translation in diverse human cell lines (increases Oct3/4 mRNA in HEK293 cells by 2.5- and 4-fold at 10 and 20 μM, respectively). It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I1 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts.
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Uses
O4I1 is a potent Oct3/4 inducer. It promotes expression and stabilization of Oct3/4, and also enhanced its transcriptional activity in human somatic cells, making it useful in regenerative medicine.
