tert-Butyl thiophen-3-ylcarbamate

Base Information

Chemical Name:tert-Butyl thiophen-3-ylcarbamate
CAS No.:19228-91-2
Molecular Formula:C9H13 N O2 S
Molecular Weight:199.274
Hs Code.:2934999090
European Community (EC) Number:694-526-3
DSSTox Substance ID:DTXSID70353030
Nikkaji Number:J462.289H
Wikidata:Q82130483
Mol file:19228-91-2.mol

Synonyms:19228-91-2;tert-Butyl thiophen-3-ylcarbamate;tert-Butyl N-(3-thienyl)carbamate;tert-butyl N-thiophen-3-ylcarbamate;tert-butyl 3-thienylcarbamate;N-Boc-3-aminothiophene;tert-butyl N-(thiophen-3-yl)carbamate;3-Aminothiophene, N-BOC protected;Carbamic acid, N-3-thienyl-, 1,1-dimethylethyl ester;(tert-butoxy)-N-(3-thienyl)carboxamide;Carbamic acid, 3-thienyl-, 1,1-dimethylethyl ester;tert-Butyl thien-3-ylcarbamate;Carbamic acid,N-3-thienyl-, 1,1-dimethylethyl ester;SCHEMBL1680647;N-Boc-3-aminothiophene, 96%;tert-Butylthiophen-3-ylcarbamate;DTXSID70353030;PRWYQCYSADTIBZ-UHFFFAOYSA-N;3-(tert-butoxycarbonylamino)thiophene;MFCD01928808;AKOS006227618;tert-Butyl-N-(thiophen-3-yl)carbamate;TERT-BUTYLN-(3-THIENYL)CARBAMATE;DS-16540;(tert-butoxy)-n-(3-thiophenyl)carboxamide;3-thiophenyl-carbamic acid tert-butyl ester;CS-0130489;FT-0695316;Thiophen-3-yl-carbamic acid tert-butyl ester;EN300-103695;A912609;AK-830/13217049;W-206417;Z1201621502

Suppliers and Price of tert-Butyl thiophen-3-ylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-ButylThiophen-3-ylcarbamate
50mg
$ 45.00

SynQuest Laboratories
3-Aminothiophene, N-Boc protected
1 g
$ 44.00

SynQuest Laboratories
3-Aminothiophene, N-Boc protected
5 g
$ 168.00

Sigma-Aldrich
N-Boc-3-aminothiophene 96%
1g
$ 195.00

Matrix Scientific
tert-Butyl N-(3-thienyl)carbamate 97%
1g
$ 354.00

Crysdot
tert-Butylthiophen-3-ylcarbamate 95+%
25g
$ 392.00

Crysdot
tert-Butylthiophen-3-ylcarbamate 95+%
10g
$ 220.00

Chemenu
N-Boc-3-aminothiophene 95%
5g
$ 131.00

Chemenu
N-Boc-3-aminothiophene 95%
10g
$ 209.00

Chemenu
N-Boc-3-aminothiophene 95%
25g
$ 374.00

Total 22 raw suppliers

Chemical Property of tert-Butyl thiophen-3-ylcarbamate

Chemical Property:

Vapor Pressure:0.0432mmHg at 25°C
Melting Point:138 °C
Boiling Point:238.1°Cat760mmHg
PKA:13.70±0.70(Predicted)
Flash Point:97.8°C
PSA：66.57000
Density:1.186g/cm³
LogP:3.16810
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:199.06669983
Heavy Atom Count:13
Complexity:189

Purity/Quality:

99%, ^*data from raw suppliers

tert-ButylThiophen-3-ylcarbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22
Safety Statements: S24/25:Avoid contact with skin and eyes.;

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CSC=C1

Technology Process of tert-Butyl thiophen-3-ylcarbamate

There total 6 articles about tert-Butyl thiophen-3-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 88-13-1
3-Thiophene carboxylic acid

: 75-65-0
tert-butyl alcohol

: 19228-91-2
tert-butyl 3-thienylcarbamate

Guidance literature:: 3-Thiophene carboxylic acid; tert-butyl alcohol; With diphenyl phosphoryl azide; triethylamine; for 3.5h; Heating / reflux;

With water; at 0 ℃;

Reference yield: 85.0%

: 872-31-1
3-Bromothiophene

: 4248-19-5
tert-butyl carbazate

: 19228-91-2
tert-butyl 3-thienylcarbamate

Guidance literature:: With di-tert-butyl{2′-isopropoxy-[1,1′-binaphthalen]-2-yl}phosphane; caesium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tert-butyl alcohol; at 100 ℃; for 20h; Inert atmosphere;
DOI:10.1021/jo3005827