1-[2-[N-(tert-Butoxycarbonyl)amino]-2-methylpropionyl]-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline

Base Information

Chemical Name:1-[2-[N-(tert-Butoxycarbonyl)amino]-2-methylpropionyl]-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline
CAS No.:957208-06-9
Molecular Formula:C₂₉H₃₁F₃N₂O₄S
Molecular Weight:560.637
Hs Code.:

Synonyms:1-[2-[N-(tert-Butoxycarbonyl)amino]-2-methylpropionyl]-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline

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Chemical Property of 1-[2-[N-(tert-Butoxycarbonyl)amino]-2-methylpropionyl]-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline

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Technology Process of 1-[2-[N-(tert-Butoxycarbonyl)amino]-2-methylpropionyl]-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline

There total 1 articles about 1-[2-[N-(tert-Butoxycarbonyl)amino]-2-methylpropionyl]-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 957203-93-9
5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline hydrochloride

: 30992-29-1
Boc-Aib-OH

: 957208-06-9
1-[2-[N-(tert-Butoxycarbonyl)amino]-2-methylpropionyl]-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline

Guidance literature:: Boc-Aib-OH; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 14h;

Reference yield:

: 957208-06-9
1-[2-[N-(tert-Butoxycarbonyl)amino]-2-methylpropionyl]-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline

: 957208-07-0
1-(2-Amino-2-methylpropionyl)-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline

Guidance literature:: 1-[2-[N-(tert-Butoxycarbonyl)amino]-2-methylpropionyl]-5-[(4-phenyl-5-trifluoromethyl-2-thienyl)methoxy]indoline; With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1h;

With sodium hydrogencarbonate; In methanol; chloroform; water;