2-(Bromomethyl)-1-(phenylsulfonyl)-1H-indole

Base Information

Chemical Name:2-(Bromomethyl)-1-(phenylsulfonyl)-1H-indole
CAS No.:337508-54-0
Molecular Formula:C15H12 Br N O2 S
Molecular Weight:350.23000
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80379903
Wikidata:Q82169931
Mol file:337508-54-0.mol

Synonyms:2-(Bromomethyl)-1-(phenylsulfonyl)-1H-indole;337508-54-0;1-(benzenesulfonyl)-2-(bromomethyl)indole;1-(benzenesulfonyl)-2-(bromomethyl)-1H-indole;SCHEMBL378955;DTXSID80379903;MFCD03086092;MS-22148;FT-0608735;J-506256

Suppliers and Price of 2-(Bromomethyl)-1-(phenylsulfonyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(BROMOMETHYL)-1-(PHENYLSULFONYL)-1H-INDOLE 95.00%
1G
$ 865.90

American Custom Chemicals Corporation
2-(BROMOMETHYL)-1-(PHENYLSULFONYL)-1H-INDOLE 95.00%
250MG
$ 657.31

Total 7 raw suppliers

Chemical Property of 2-(Bromomethyl)-1-(phenylsulfonyl)-1H-indole

Chemical Property:

Vapor Pressure:9.26E-11mmHg at 25°C
Melting Point:118oC
Boiling Point:516.1oC at 760 mmHg
Flash Point:265.9oC
PSA：47.45000
Density:1.5g/cm3
LogP:4.85400
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:348.97721
Heavy Atom Count:20
Complexity:428

Purity/Quality:

98%min ^*data from raw suppliers

2-(BROMOMETHYL)-1-(PHENYLSULFONYL)-1H-INDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes: C:Corrosive;
Statements: R34:Causes burns.;
Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3C=C2CBr

Technology Process of 2-(Bromomethyl)-1-(phenylsulfonyl)-1H-indole

There total 3 articles about 2-(Bromomethyl)-1-(phenylsulfonyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73282-11-8
<1-(phenylsulfonyl)indol-2-yl>methanol

: 337508-54-0
2-(N-benzenesulfonyl)indolyl methyl bromide

Guidance literature:: With sulfuric acid; hydrogen bromide; In dichloromethane; for 1.5h;
DOI:10.1021/jm020901d

Reference yield:

: 40899-71-6
1-benzenesulfonylindole

: 337508-54-0
2-(N-benzenesulfonyl)indolyl methyl bromide

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C

1.2: tetrahydrofuran / 2 h / -78 °C

2.1: DIBAL-H / tetrahydrofuran; hexane / 1 h / -78 °C

3.1: aq. HBr; H₂SO₄ / CH₂Cl₂ / 1.5 h

With n-butyllithium; sulfuric acid; hydrogen bromide; diisobutylaluminium hydride; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jm020901d

Reference yield:

: 80360-23-2
1-(phenylsulfonyl)-1H-indole-2-carbaldehyde

: 337508-54-0
2-(N-benzenesulfonyl)indolyl methyl bromide

Guidance literature:: Multi-step reaction with 2 steps

1: DIBAL-H / tetrahydrofuran; hexane / 1 h / -78 °C

2: aq. HBr; H₂SO₄ / CH₂Cl₂ / 1.5 h

With sulfuric acid; hydrogen bromide; diisobutylaluminium hydride; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jm020901d