4-(1,3-Oxazol-5-yl)benzoic Acid

Base Information

Chemical Name:4-(1,3-Oxazol-5-yl)benzoic Acid
CAS No.:250161-45-6
Molecular Formula:C10H7NO3
Molecular Weight:189.17
Hs Code.:2934999090
European Community (EC) Number:630-251-7
DSSTox Substance ID:DTXSID20380058
Wikidata:Q82170087
ChEMBL ID:CHEMBL3354470
Mol file:250161-45-6.mol

Synonyms:4-(1,3-Oxazol-5-yl)benzoic Acid;250161-45-6;4-(5-Oxazolyl)benzoic Acid;4-(Oxazol-5-yl)benzoic acid;Benzoic acid, 4-(5-oxazolyl)-;MFCD02682033;4-(5-Oxazolyl)benzoicAcid;4-(Oxazol-5-yl)benzoicacid;SDCCGMLS-0065980.P001;4-oxazol-5-yl-benzoic acid;Oprea1_403666;AMY464;SCHEMBL1010247;CHEMBL3354470;DTXSID20380058;MCPBXFWYUHYSIZ-UHFFFAOYSA-N;4-(l,3-oxazol-5-yl)benzoic acid;4-(1,3-oxazol-5-yl) benzoic acid;AKOS006227620;AC-7135;PS-4281;SY004185;CS-0083897;FT-0616459;EN300-48602;A877740;AN-584/43485242;W-206919;Z566015354

Suppliers and Price of 4-(1,3-Oxazol-5-yl)benzoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(1,3-Oxazol-5-yl)benzoicAcid
25mg
$ 45.00

SynQuest Laboratories
4-(1,3-Oxazol-5-yl)benzoic acid
250 mg
$ 32.00

Matrix Scientific
4-(1,3-Oxazol-5-yl)benzoic acid 97%
1g
$ 360.00

Crysdot
4-(Oxazol-5-yl)benzoicacid 97%
5g
$ 377.00

Chemenu
4-(1,3-Oxazol-5-yl)benzoicacid 96%
5g
$ 353.00

Atlantic Research Chemicals
4-(1,3-Oxazol-5-yl)benzoicacid 95%
1gm:
$ 137.85

Apolloscientific
4-(1,3-Oxazol-5-yl)benzoicacid
250mg
$ 29.00

American Custom Chemicals Corporation
4-(1,3-OXAZOL-5-YL)BENZOIC ACID 95.00%
5G
$ 1168.42

American Custom Chemicals Corporation
4-(1,3-OXAZOL-5-YL)BENZOIC ACID 95.00%
2.5G
$ 983.88

American Custom Chemicals Corporation
4-(1,3-OXAZOL-5-YL)BENZOIC ACID 95.00%
1G
$ 721.57

Total 19 raw suppliers

Chemical Property of 4-(1,3-Oxazol-5-yl)benzoic Acid

Chemical Property:

Melting Point:301-302 °C
Boiling Point:390.3 °C at 760 mmHg
PKA:3.86±0.10(Predicted)
Flash Point:189.8 °C
PSA：63.33000
Density:1.32 g/cm³
LogP:2.03980
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:189.042593085
Heavy Atom Count:14
Complexity:211

Purity/Quality:

99%, ^*data from raw suppliers

4-(1,3-Oxazol-5-yl)benzoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CN=CO2)C(=O)O

Technology Process of 4-(1,3-Oxazol-5-yl)benzoic Acid

There total 2 articles about 4-(1,3-Oxazol-5-yl)benzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 179057-14-8
4-oxazol-5-ylbenzoic acid methyl ester

: 250161-45-6
4-(1,3-oxazol-5-yl)benzoic acid

Guidance literature:: With sodium hydroxide; In methanol; water; at 20 ℃; for 24h;
DOI:10.1016/j.bmcl.2014.11.042

Reference yield:

: 1571-08-0
methyl 4-formylbenzoate

: 250161-45-6
4-(1,3-oxazol-5-yl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / methanol / 3 h / Inert atmosphere; Reflux

2: sodium hydroxide / water; methanol / 1.5 h / Inert atmosphere

With potassium carbonate; sodium hydroxide; In methanol; water;
DOI:10.1080/14756366.2021.1941920

Reference yield: 80.0%

: 250161-45-6
4-(1,3-oxazol-5-yl)benzoic acid

: 335255-43-1
tert-butyl 2-amino-4-(thiophen-2-yl)phenylcarbamate

: tert-butyl (2-(4-(oxazol-5-yl)benzamido)-4-(thiophen-2-yl)phenyl)carbamate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1080/14756366.2021.1941920