2‐(4‐fluorobenzyl)‐3‐hydroxy propanenitrile

Base Information

Chemical Name:2‐(4‐fluorobenzyl)‐3‐hydroxy propanenitrile
CAS No.:890147-29-2
Molecular Formula:C₁₀H₁₀FNO
Molecular Weight:179.194
Hs Code.:

Synonyms:2‐(4‐fluorobenzyl)‐3‐hydroxy propanenitrile

Suppliers and Price of 2‐(4‐fluorobenzyl)‐3‐hydroxy propanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 2‐(4‐fluorobenzyl)‐3‐hydroxy propanenitrile

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Technology Process of 2‐(4‐fluorobenzyl)‐3‐hydroxy propanenitrile

There total 2 articles about 2‐(4‐fluorobenzyl)‐3‐hydroxy propanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50737-52-5,18861-57-9
ethyl 2-cyano-3-(4-fluorophenyl)acrylate

: 890147-29-2
2‐(4‐fluorobenzyl)‐3‐hydroxy propanenitrile

Guidance literature:: With sodium tetrahydroborate; In water; at 45 ℃; for 1h;
DOI:10.1002/aoc.4800

Reference yield:

: 32691-93-3
α,α-dimethoxy-4-fluorotoluene

: 890147-29-2
2‐(4‐fluorobenzyl)‐3‐hydroxy propanenitrile

Guidance literature:: Multi-step reaction with 2 steps

1: Ni‐Pd nanoparticles supported on poly (styrenesulfonic acid‐n‐vinylimidazole)/KIT‐6 / water / 5 h / 45 °C

2: sodium tetrahydroborate / water / 1 h / 45 °C

With sodium tetrahydroborate; In water; 1: |Knoevenagel Condensation;
DOI:10.1002/aoc.4800