2-brom-2-(4-pyridyl)-1-phenyl-1-ethanon-hydrobromid

Base Information

• Chemical Name: 2-brom-2-(4-pyridyl)-1-phenyl-1-ethanon-hydrobromid
• CAS No.: 99466-56-5
• Molecular Formula: BrH*C₁₃H₁₀BrNO
• Molecular Weight: 357.044
• Mol file: 99466-56-5.mol

Synonyms:2-brom-2-(4-pyridyl)-1-phenyl-1-ethanon-hydrobromid

Chemical Property of 2-brom-2-(4-pyridyl)-1-phenyl-1-ethanon-hydrobromid

Chemical Property:

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-brom-2-(4-pyridyl)-1-phenyl-1-ethanon-hydrobromid

There total 8 articles about 2-brom-2-(4-pyridyl)-1-phenyl-1-ethanon-hydrobromid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-phenyl-2-(4-pyridinyl)ethanone (1620-55-9) → 2-brom-2-(4-pyridyl)-1-phenyl-1-ethanon-hydrobromid (99466-56-5)

Guidance literature:

With bromine; In acetic acid; for 2h; Ambient temperature;

Reference yield:

4-(phenylethynyl)pyridine (13295-94-8) → 2-brom-2-(4-pyridyl)-1-phenyl-1-ethanon-hydrobromid (99466-56-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid; water

2: acetic acid; bromine

With sulfuric acid; water; bromine; acetic acid;

DOI:10.1021/ja01192a009

Reference yield:

4-(α-bromo-styryl)-pyridine (408320-71-8) → 2-brom-2-(4-pyridyl)-1-phenyl-1-ethanon-hydrobromid (99466-56-5)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanolic KOH-solution

2: sulfuric acid; water

3: acetic acid; bromine

With potassium hydroxide; sulfuric acid; water; bromine; acetic acid;

DOI:10.1021/ja01192a009

upstream raw materials:

1-phenyl-2-(4-pyridinyl)ethanone

phenyl(trimethylsiloxy)acetonitrile

4-picolylchloride hydrochloride

4-(phenylethynyl)pyridine

Downstream raw materials:

5-phenyl-6-(4-pyridyl)-2,3-dihydroimidazo<2,1-b>thiazole

Refernces

• 1、 -. "Adenosine A3 receptor antagonists". . . Retrieved 2008/06/13.