5-tert-butyl-1-(4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl)-2-hydroxybenzene

Base Information

• Chemical Name: 5-tert-butyl-1-(4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl)-2-hydroxybenzene
• CAS No.: 118967-78-5
• Molecular Formula: C₂₀H₂₆O₆
• Molecular Weight: 362.423
• Mol file: 118967-78-5.mol

Synonyms:5-tert-butyl-1-(4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl)-2-hydroxybenzene

Chemical Property of 5-tert-butyl-1-(4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl)-2-hydroxybenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-tert-butyl-1-(4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl)-2-hydroxybenzene

There total 2 articles about 5-tert-butyl-1-(4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl)-2-hydroxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

(4-tert-Butylphenoxy)magnesium bromide (36359-99-6) + D-glucal triacetate (2873-29-2) → 5-tert-butyl-1-(4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl)-2-hydroxybenzene (118967-78-5) + 4-t-butylphenyl4, 6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside (171082-23-8)

Guidance literature:

In dichloromethane; at 0 ℃; sonication;

DOI:10.1002/1099-0690(200301)2003:1<106::AID-EJOC106>3.0.CO;2-7

Reference yield:

para-tert-butylphenol (98-54-4) + D-glucal triacetate (2873-29-2) → 5-tert-butyl-1-(4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl)-2-hydroxybenzene (118967-78-5)

Guidance literature:

With ethylmagnesium bromide; Yield given. Multistep reaction; 1) diethyl ether, 10 min, 2) methylene dichloride, 8 h, 20 deg C, irradiation;

DOI:10.1016/0040-4039(88)85152-9

upstream raw materials:

para-tert-butylphenol

D-glucal triacetate

(4-tert-Butylphenoxy)magnesium bromide