Technology Process of 13,14,15,16-tetranorlabd-8(17)-en-12-ol
There total 2 articles about 13,14,15,16-tetranorlabd-8(17)-en-12-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: KMnO4; MgSO4 / acetone / 20 °C
2: 66 percent / oxygen / 1,2-dimethoxy-ethane / 4 h / 20 °C
3: 95 percent / LiAlH4 / tetrahydrofuran / 2 h / Heating
With
potassium permanganate; lithium aluminium tetrahydride; oxygen; magnesium sulfate;
In
tetrahydrofuran; 1,2-dimethoxyethane; acetone;
DOI:10.1080/00397910500377172
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 5 g / t-butyl hydroperoxide, vanadyl acetylacetonate / benzene
2: 4.7 g / LiAlH4 / diethyl ether / 1 h / Heating
3: 3.5 g / sodium periodate / H2O; methanol / Ambient temperature
4: 3.2 g / sodium hypobromite / dioxane
5: 0.57 g / LDA, diperoxo(oxohexamethylphosphoramido)molybdenum(VI) / tetrahydrofuran; hexane / 2 h / -5 °C
6: 0.6 g / LiAlH4 / diethyl ether / 1 h / Heating
7: 0.1 g / sodium periodate / H2O; methanol / Ambient temperature
8: 0.09 g / LiAlH4 / diethyl ether / 0.5 h / Heating
With
tert.-butylhydroperoxide; sodium periodate; lithium aluminium tetrahydride; sodium hypobromide; diperoxo(oxohexamethylphosphoramido)molybdenum(VI); vanadyl acetylacetonate; lithium diisopropyl amide;
In
tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; hexane; water; benzene;
DOI:10.1071/CH9880711
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Jones reagent
2: dmap / dichloromethane / 10 h / 20 °C
With
dmap; Jones reagent;
In
dichloromethane;
DOI:10.1055/s-0032-1318253
