ethyl (1R,2S)-1-(2-(3-(tert-butoxycarbonylamino)-5-chloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetamido)-2-vinylcyclopropanecarboxylate

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Chemical Name:ethyl (1R,2S)-1-(2-(3-(tert-butoxycarbonylamino)-5-chloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetamido)-2-vinylcyclopropanecarboxylate
CAS No.:1178896-09-7
Molecular Formula:C₂₆H₃₁ClN₄O₆
Molecular Weight:531.008
Hs Code.:

Synonyms:ethyl (1R,2S)-1-(2-(3-(tert-butoxycarbonylamino)-5-chloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetamido)-2-vinylcyclopropanecarboxylate

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Chemical Property of ethyl (1R,2S)-1-(2-(3-(tert-butoxycarbonylamino)-5-chloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetamido)-2-vinylcyclopropanecarboxylate

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Technology Process of ethyl (1R,2S)-1-(2-(3-(tert-butoxycarbonylamino)-5-chloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetamido)-2-vinylcyclopropanecarboxylate

There total 1 articles about ethyl (1R,2S)-1-(2-(3-(tert-butoxycarbonylamino)-5-chloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetamido)-2-vinylcyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

: 259214-54-5,259214-56-7
ethyl (1R,2S)-1-amino-2-vinylcyclopropanecarboxylate hydrochloride

: 1178896-08-6,1251933-01-3
2-(3-(t-butoxycarbonylamino)-5-chloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester

: 1178896-09-7
ethyl (1R,2S)-1-(2-(3-(tert-butoxycarbonylamino)-5-chloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetamido)-2-vinylcyclopropanecarboxylate

Guidance literature:: 2-(3-(t-butoxycarbonylamino)-5-chloro-6-methyl-2-oxopyrazin-1(2H)-yl)-2-phenylacetic acid methyl ester; With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 7h;

ethyl (1R,2S)-1-amino-2-vinylcyclopropanecarboxylate hydrochloride; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 120h;
DOI:10.1039/b905501k