4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal

Base Information

• Chemical Name: 4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal
• CAS No.: 1044747-30-9
• Molecular Formula: C₃₇H₅₁NO₁₂
• Molecular Weight: 701.811
• Mol file: 1044747-30-9.mol

Synonyms:4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal

Chemical Property of 4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal

There total 1 articles about 4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-O-[2-deoxy-3,4-O-isopropylidene-2-oximino-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal (1044747-29-6) + benzyl bromide (100-39-0) → 4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal (1044747-30-9)

Guidance literature:

With potassium hydroxide; 18-crown-6 ether; In tetrahydrofuran; water; at 20 ℃; for 4h;

DOI:10.1080/07328300802030845

Reference yield: 74.0%

4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal (1044747-30-9) + acetic anhydride (108-24-7) → C32H51NO12 (1044747-35-4) + 4-O-(2-acetamido-6-O-benzyl-2-deoxy-3,4-O-isopropylidene-β-D-talopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal (791837-61-1)

Guidance literature:

4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal; With lithium aluminium tetrahydride; In diethyl ether; for 192h; Heating;

acetic anhydride; In methanol; at 20 ℃; Further stages.;

DOI:10.1080/07328300802030845

Reference yield:

4-O-[6-O-benzyl-2-benzyloxyimino-2-deoxy-3,4-O-isopropylidene-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal (1044747-30-9) → C30H47NO11

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 72h; Heating;

DOI:10.1080/07328300802030845

upstream raw materials:

4-O-[2-deoxy-3,4-O-isopropylidene-2-oximino-β-D-lyxo-hexopyranosyl]-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal

benzyl bromide

Downstream raw materials:

C₃₂H₅₁NO₁₂

4-O-(2-acetamido-6-O-benzyl-2-deoxy-3,4-O-isopropylidene-β-D-talopyranosyl)-2,3:5,6-di-O-isopropylidene-aldehydo-D-glucose dimethyl acetal