phenethyl 1-(triphenylsilyl)vinyl ketone

Base Information

• Chemical Name: phenethyl 1-(triphenylsilyl)vinyl ketone
• CAS No.: 1256237-25-8
• Molecular Formula: C₂₉H₂₆OSi
• Molecular Weight: 418.61
• Mol file: 1256237-25-8.mol

Synonyms:phenethyl 1-(triphenylsilyl)vinyl ketone

Chemical Property of phenethyl 1-(triphenylsilyl)vinyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenethyl 1-(triphenylsilyl)vinyl ketone

There total 1 articles about phenethyl 1-(triphenylsilyl)vinyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-phenyl-2-(triphenylsilyl)pent-1-en-3-ol (719283-07-5) → phenethyl 1-(triphenylsilyl)vinyl ketone (1256237-25-8)

Guidance literature:

DOI:10.1002/anie.201003152

Reference yield: 71.0%

phenethyl 1-(triphenylsilyl)vinyl ketone (1256237-25-8) + CH3Cu*C4H9O(1-)*Cu(1+) + 3-Chloro-2-methylpropene (563-47-3) → (4Z)-4-ethyl-2-methyl-7-phenyl-5-(triphenylsiloxy)-1,4-heptadiene (1256237-19-0)

Guidance literature:

phenethyl 1-(triphenylsilyl)vinyl ketone; CH₃Cu*C₄H₉O^(1-)*Cu⁽¹⁺⁾; In tetrahydrofuran; at 0 ℃; for 2h;

With N,N-dimethyl-formamide; In tetrahydrofuran; at 70 ℃; for 0.5h;

3-Chloro-2-methylpropene; In tetrahydrofuran; N,N-dimethyl-formamide; at 70 ℃; for 4h; stereoselective reaction;

DOI:10.1002/anie.201003152

Reference yield: 70.0%

phenethyl 1-(triphenylsilyl)vinyl ketone (1256237-25-8) + C4H9O(1-)*C4H11CuSi*Cu(1+) + 3-Chloro-2-methylpropene (563-47-3) → (4Z)-2-methyl-7-phenyl-4-(trimethylsilylethyl)-5-(triphenylsiloxy)-1,4-heptadiene

Guidance literature:

phenethyl 1-(triphenylsilyl)vinyl ketone; C₄H₉O^(1-)*C₄H₁₁CuSi*Cu⁽¹⁺⁾; In tetrahydrofuran; at 0 ℃; for 2h;

With N,N-dimethyl-formamide; In tetrahydrofuran; at 70 ℃; for 0.5h;

3-Chloro-2-methylpropene; In tetrahydrofuran; N,N-dimethyl-formamide; at 70 ℃; for 4h; stereoselective reaction;

DOI:10.1002/anie.201003152

upstream raw materials:

5-phenyl-2-(triphenylsilyl)pent-1-en-3-ol

Downstream raw materials:

(4Z)-4-ethyl-2-methyl-7-phenyl-5-(triphenylsiloxy)-1,4-heptadiene

(3Z)-4-benzyl-6-methyl-1-phenyl-3-(triphenylsiloxy)-3-heptene