C₁₈H₂₀FN₅O

Base Information

Chemical Name:C₁₈H₂₀FN₅O
CAS No.:1227918-89-9
Molecular Formula:C₁₈H₂₀FN₅O
Molecular Weight:341.388
Hs Code.:

C<sub>18</sub>H<sub>20</sub>FN<sub>5</sub>O

Synonyms:C₁₈H₂₀FN₅O

Suppliers and Price of C₁₈H₂₀FN₅O

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Chemical Property of C₁₈H₂₀FN₅O

Chemical Property:

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Technology Process of C₁₈H₂₀FN₅O

There total 3 articles about C₁₈H₂₀FN₅O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4276-09-9,473-75-6
(R)-2-amino-3-methylbutanol

: 1227918-89-9
C₁₈H₂₀FN₅O

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / toluene / 0 °C

1.2: 90 - 110 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 70 °C

3.1: methanol; ethanol / 50 - 100 °C

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / 1,4-dioxane; water / 95 °C

With lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride; sodium hydrogencarbonate; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; water; toluene; 4.1: Suzuki coupling;
DOI:10.1021/jm101527u

Reference yield:

: 1007113-31-6
(R)-5-isopropylmorpholin-3-one

: 1227918-89-9
C₁₈H₂₀FN₅O

Guidance literature:: Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 70 °C

2: methanol; ethanol / 50 - 100 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / 1,4-dioxane; water / 95 °C

With lithium aluminium tetrahydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; In tetrahydrofuran; 1,4-dioxane; methanol; ethanol; water; 3: Suzuki coupling;
DOI:10.1021/jm101527u

Reference yield:

: 74572-01-3
(R)-3-isopropylmorpholine

: 1227918-89-9
C₁₈H₂₀FN₅O

Guidance literature:: Multi-step reaction with 2 steps

1: methanol; ethanol / 50 - 100 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate / 1,4-dioxane; water / 95 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; In 1,4-dioxane; methanol; ethanol; water; 2: Suzuki coupling;
DOI:10.1021/jm101527u