5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

Base Information

Chemical Name:5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine
CAS No.:1004764-05-9
Molecular Formula:C₁₇H₁₉ClN₂O₂S
Molecular Weight:350.869
Hs Code.:

Synonyms:5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

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Chemical Property of 5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

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Technology Process of 5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

There total 1 articles about 5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1004764-02-6
2-{4-[(3-chloropropyl)oxy]phenyl}-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

: 75-36-5
acetyl chloride

: 1004764-05-9
5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 2h;

Reference yield: 52.0%

: 1004764-05-9
5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

: 765-38-8
2-methyl-1-pyrrolidine

: 5-acetyl-2-{4-[3-(2-methylpyrrolidin-1-yl)propoxy]phenyl}-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

Guidance literature:: With potassium carbonate; sodium iodide; In acetonitrile; at 90 ℃; for 24h;

Reference yield: 36.0%

: 1004764-05-9
5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

: 109-05-7,3000-79-1
2-Methylpiperidin

: 5-acetyl-2-{4-[3-(2-methylpiperidin-1-yl)propoxy]phenyl}-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine

Guidance literature:: 5-acetyl-2-[4-(3-chloropropoxy)phenyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine; 2-Methylpiperidin; In acetonitrile; at 120 ℃; for 5h; Microwave irradiation;

With hydrogenchloride; In water;

With sodium hydroxide; In water; ethyl acetate; pH=13;