6-Chlorobenzo[d]isoxazol-3-ol

Base Information

Chemical Name:6-Chlorobenzo[d]isoxazol-3-ol
CAS No.:61977-29-5
Molecular Formula:C7H4ClNO2
Molecular Weight:169.57
Hs Code.:2934999090
European Community (EC) Number:687-918-0
DSSTox Substance ID:DTXSID70381878
Nikkaji Number:J3.021.464A
Wikidata:Q72517200
Pharos Ligand ID:PRCTNU3JZQ4M
ChEMBL ID:CHEMBL445990
Mol file:61977-29-5.mol

Synonyms:6-chlorobenzo[d]isoxazol-3-ol;61977-29-5;CBIO;6-Chloro-1,2-benzisoxazol-3-ol;6-Chloro-3-hydroxy-1,2-benzisoxazole;6-chloro-1,2-benzoxazol-3-one;6-CHLORO-1,2-BENZISOXAZOL-3(2H)-ONE;6-chloro-1,2-benzoxazol-3-ol;CHEMBL445990;MFCD00125033;6-chlorobenzo(d)isoxazol-3-ol;1,2-Benzisoxazol-3(2H)-one, 6-chloro-;6-Chlorobenzisoxazol-3(2H)-one;1,2-Benzisoxazol-3(2H)-one,6-chloro-;MLS000850688;SCHEMBL481926;6-Chloro-3-hydroxybenzisoxazole;6-Chloro-benzo[d]isoxazol-3-ol;BDBM23174;3-hydroxy-6-chloro-benzisoxazole;DTXSID70381878;CHEBI:194636;SJAPSPJRTQCDNO-UHFFFAOYSA-N;HMS2790M22;HMS3741O11;CBIO, >=95% (HPLC);CCG-1741;BDBM50170230;GEO-03212;6-Chlorobenzo[d]isoxazol-3(2H)-one;AKOS006230032;6-Chloro-1,2-benzoisoxazole-3(2H)-one;PD129399;SMR000456705;SY104108;TS-02303;6-chlorobenzo[d]isoxazol-3-ol, AldrichCPR;CS-0063922;FT-0621064;6-chloro-2,3-dihydro-1,2-benzoxazol-3-one;EN300-318802;A833514;SR-01000641124-1

Suppliers and Price of 6-Chlorobenzo[d]isoxazol-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-1,2-benzisoxazol-3(2H)-one
1g
$ 1175.00

Sigma-Aldrich
D-Amino Acid Oxidase Inhibitor II, CBIO
50mg
$ 92.60

Matrix Scientific
6-Chloro-1,2-benzisoxazol-3-ol 97%
1g
$ 249.00

ChemScene
6-Chlorobenzo[d]isoxazol-3(2H)-one 99.85%
250mg
$ 65.00

ChemScene
6-Chlorobenzo[d]isoxazol-3(2H)-one 99.85%
1g
$ 156.00

ChemScene
6-Chlorobenzo[d]isoxazol-3(2H)-one 99.85%
5g
$ 540.00

Chemenu
6-Chloro-1,2-benzisoxazol-3-ol 95%
5g
$ 679.00

Chemcia Scientific
6-Bromo-benzo[d]isoxazol-3-ol 95%
5 G
$ 1050.00

Chemcia Scientific
6-Bromo-benzo[d]isoxazol-3-ol 95%
1 G
$ 350.00

Atlantic Research Chemicals
6-Chloro-1,2-benzisoxazol-3-ol 95%
1gm:
$ 134.31

Total 27 raw suppliers

Chemical Property of 6-Chlorobenzo[d]isoxazol-3-ol

Chemical Property:

Appearance/Colour:gray solid
Vapor Pressure:5.65E-05mmHg at 25°C
Melting Point:218-220 °C
Refractive Index:1.603
Boiling Point:336.7 °C at 760 mmHg
PKA:13.14±0.20(Predicted)
Flash Point:157.4 °C
PSA：46.26000
Density:1.486 g/cm³
LogP:2.18680
Storage Temp.:room temp
Solubility.:DMSO: soluble15mg/mL (clear solution)
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:168.9930561
Heavy Atom Count:11
Complexity:185

Purity/Quality:

99%, ^*data from raw suppliers

6-Chloro-1,2-benzisoxazol-3(2H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-22-41-37/38
Safety Statements: 26-36/37/39-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1Cl)ONC2=O
Uses 6-Chloro-1,2-benzisoxazol-3(2H)-one is a D-amino acid oxidase reversible inhibitor.

Technology Process of 6-Chlorobenzo[d]isoxazol-3-ol

There total 8 articles about 6-Chlorobenzo[d]isoxazol-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 61799-78-8
4-chloro-N,2-dihydroxybenzamide

: 61977-29-5
6-chloro-benzo[d]isoxazol-3-ol

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 0.533333h; Inert atmosphere;
DOI:10.1016/j.tetlet.2016.10.045