(1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate

Base Information

• Chemical Name: (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate
• CAS No.: 137761-03-6
• Molecular Formula: C₂₄H₂₉ClO₃S
• Molecular Weight: 433.011
• Mol file: 137761-03-6.mol

Synonyms:(1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate

Chemical Property of (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate

There total 1 articles about (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(-)-8-phenylmenthol (65253-04-5) + (S)-(-)-<(4-Chlorophenyl)sulfinyl>acetic acid (125706-42-5) → (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate (137761-03-6)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; 1) -78 deg C, 0.5 h, 2) -25 deg C, 16 h;

DOI:10.1016/S0040-4020(01)82313-9

Reference yield: 82.0%

pentanal (110-62-3) + (1R,2S,5R)-8-phenylmenthyl (S)-4-chlorophenylsulfinylacetate (137761-03-6) → E-(1R,2S,5R)-8-phenylmenthyl 4-hydroxyhept-2-enoate (137761-08-1,137821-29-5)

Guidance literature:

With piperidine; In acetonitrile; at 25 ℃; for 49h;

DOI:10.1016/S0040-4020(01)82313-9

upstream raw materials:

(-)-8-phenylmenthol

(S)-(-)-<(4-Chlorophenyl)sulfinyl>acetic acid

Downstream raw materials:

E-(1R,2S,5R)-8-phenylmenthyl 4-hydroxyhept-2-enoate