(4R)-4-t-butoxycarbonylamino-5-(methanesulfonyloxy)pentanoic acid benzyl ester

Base Information

Chemical Name:(4R)-4-t-butoxycarbonylamino-5-(methanesulfonyloxy)pentanoic acid benzyl ester
CAS No.:342908-13-8
Molecular Formula:C₁₈H₂₇NO₇S
Molecular Weight:401.481
Hs Code.:

Synonyms:(4R)-4-t-butoxycarbonylamino-5-(methanesulfonyloxy)pentanoic acid benzyl ester

Suppliers and Price of (4R)-4-t-butoxycarbonylamino-5-(methanesulfonyloxy)pentanoic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (4R)-4-t-butoxycarbonylamino-5-(methanesulfonyloxy)pentanoic acid benzyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of (4R)-4-t-butoxycarbonylamino-5-(methanesulfonyloxy)pentanoic acid benzyl ester

There total 2 articles about (4R)-4-t-butoxycarbonylamino-5-(methanesulfonyloxy)pentanoic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 124-63-0
methanesulfonyl chloride

: 195434-34-5
(4R)-4-t-butoxycarbonylamino-5-hydroxypentanoic acid benzyl ester

: 342908-13-8
(4R)-4-t-butoxycarbonylamino-5-(methanesulfonyloxy)pentanoic acid benzyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃;
DOI:10.1016/j.bmc.2004.12.033

Reference yield:

: 35793-73-8
N-(tert-butyloxycarbonyl)-γ-benzyl-D-glutamic acid

: 342908-13-8
(4R)-4-t-butoxycarbonylamino-5-(methanesulfonyloxy)pentanoic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethyl chloroformate; N-methylmorpholine / tetrahydrofuran

1.2: 10.9 g / NaBH₄ / tetrahydrofuran; H₂O / 0.05 h / cooling

2.1: triethylamine / CH₂Cl₂ / 0 °C

With 4-methyl-morpholine; chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2004.12.033