(αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2,5-dimethoxybenzeneacetic acid

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Chemical Name:(αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2,5-dimethoxybenzeneacetic acid
CAS No.:1450604-62-2
Molecular Formula:C₂₈H₂₅NO₆
Molecular Weight:471.51
Hs Code.:

Synonyms:(αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2,5-dimethoxybenzeneacetic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2,5-dimethoxybenzeneacetic acid

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Technology Process of (αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2,5-dimethoxybenzeneacetic acid

There total 1 articles about (αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2,5-dimethoxybenzeneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 6953-22-6
5-benzyloxyindole-3-carboxaldehyde

: 1758-25-4
(2,5-dimethoxyphenyl)acetic acid

: 1450604-62-2
(αE)-α-[[1-acetyl-5-(phenylmethoxy)-1H-indol-3-yl]methylene]-2,5-dimethoxybenzeneacetic acid

Guidance literature:: 5-benzyloxyindole-3-carboxaldehyde; (2,5-dimethoxyphenyl)acetic acid; With acetic anhydride; triethylamine; at 130 ℃; for 6h;

With water; In tetrahydrofuran; ethanol; at 22 - 90 ℃; for 16h;
DOI:10.1016/j.bmc.2013.06.030