C₂₅H₄₁PSi

Base Information

• Chemical Name: C₂₅H₄₁PSi
• CAS No.: 1416169-93-1
• Molecular Formula: C₂₅H₄₁PSi
• Molecular Weight: 400.66
• Mol file: 1416169-93-1.mol

Synonyms:C₂₅H₄₁PSi

Chemical Property of C₂₅H₄₁PSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₂₅H₄₁PSi

There total 2 articles about C₂₅H₄₁PSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

trimethylsilylacetylene (1066-54-2) + (Z)-2-bromo-1-(2,4,6-tri-t-butylphenyl)-1-phosphapropene (100281-28-5,100281-29-6,100281-32-1) → C25H41PSi (1416169-93-1)

Guidance literature:

With pyridine; copper(l) iodide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; for 0.0833333h; Reagent/catalyst; Solvent; Time; Inert atmosphere;

DOI:10.1002/zaac.201200324

Reference yield:

[(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine] (100281-23-0) → C25H41PSi (1416169-93-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; diethyl ether; pentane / 0.5 h / -120 °C / Inert atmosphere

1.2: 2.5 h / -120 - 20 °C / Inert atmosphere

2.1: copper(l) iodide; triethylamine; pyridine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / tetrahydrofuran; N,N-dimethyl-formamide / 0.08 h / Inert atmosphere

With pyridine; copper(l) iodide; n-butyllithium; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; triethylamine; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; pentane; 2.1: |Sonogashira Cross-Coupling;

DOI:10.1002/zaac.201200324

Reference yield: 84.0%

(tetrahydrothiophene)gold(I) chloride (39929-21-0) + C25H41PSi (1416169-93-1) → C25H41AuClPSi

Guidance literature:

In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201504834

upstream raw materials:

trimethylsilylacetylene

(Z)-2-bromo-1-(2,4,6-tri-t-butylphenyl)-1-phosphapropene

[(dibromomethylene)(2,4,6-tri-tertbutylphenyl)phosphine]

Downstream raw materials:

C₄₄H₆₄P₂

Refernces