cyclohex-2-enyl-[2]thienyl-acetic acid-(2-diethylamino-ethyl ester)

Base Information

• Chemical Name: cyclohex-2-enyl-[2]thienyl-acetic acid-(2-diethylamino-ethyl ester)
• CAS No.: 853992-73-1
• Molecular Formula: C₁₈H₂₇NO₂S
• Molecular Weight: 321.484
• Mol file: 853992-73-1.mol

Synonyms:cyclohex-2-enyl-[2]thienyl-acetic acid-(2-diethylamino-ethyl ester)

Chemical Property of cyclohex-2-enyl-[2]thienyl-acetic acid-(2-diethylamino-ethyl ester)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohex-2-enyl-[2]thienyl-acetic acid-(2-diethylamino-ethyl ester)

There total 7 articles about cyclohex-2-enyl-[2]thienyl-acetic acid-(2-diethylamino-ethyl ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rac-3-bromocyclohexene (1521-51-3,113667-32-6) → cyclohex-2-enyl-[2]thienyl-acetic acid-(2-diethylamino-ethyl ester) (853992-73-1)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium amide; toluene

2: aq.-ethanolic KOH-solution

3: 1,2-dichloro-ethane; methanesulfonic acid

4: sodium; xylene / Entfernen des entstehenden Methanols

With potassium hydroxide; methanesulfonic acid; sodium; sodium amide; 1,2-dichloro-ethane; toluene; xylene;

DOI:10.1021/ja01133a004

Reference yield:

2-cyanomethylthiophene (20893-30-5) → cyclohex-2-enyl-[2]thienyl-acetic acid-(2-diethylamino-ethyl ester) (853992-73-1)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium amide; toluene

2: aq.-ethanolic KOH-solution

3: 1,2-dichloro-ethane; methanesulfonic acid

4: sodium; xylene / Entfernen des entstehenden Methanols

With potassium hydroxide; methanesulfonic acid; sodium; sodium amide; 1,2-dichloro-ethane; toluene; xylene;

DOI:10.1021/ja01133a004

Reference yield:

cyclohex-2-enyl-[2]thienyl-acetic acid (847544-62-1) + 2-(diethylamino)ethyl chloride (100-35-6) → cyclohex-2-enyl-[2]thienyl-acetic acid-(2-diethylamino-ethyl ester) (853992-73-1)

Guidance literature:

With isopropyl alcohol;

DOI:10.1021/ja01131a059

upstream raw materials:

2-(Diethylamino)ethanol

cyclohex-2-enyl-[2]thienyl-acetic acid

2-(diethylamino)ethyl chloride

2-cyanomethylthiophene