Technology Process of 2-[(S)-1-phenylmethyl-2-methoxyethylimino]-aci-1-nitrocyclohexane
There total 1 articles about 2-[(S)-1-phenylmethyl-2-methoxyethylimino]-aci-1-nitrocyclohexane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-[(S)-1-phenylmethyl-2-methoxyethylimino]-aci-1-nitrocyclohexane;
With
sec.-butyllithium;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;
at -78 ℃;
Inert atmosphere;
allyl iodid;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;
at -90 - 10 ℃;
Inert atmosphere;
With
acetic acid;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; water;
optical yield given as %de;
diastereoselective reaction;
DOI:10.1021/jo801790r
- Guidance literature:
-
2-[(S)-1-phenylmethyl-2-methoxyethylimino]-aci-1-nitrocyclohexane;
With
sec.-butyllithium;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;
at -78 ℃;
Inert atmosphere;
1-iodo-butane;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide;
at -90 - 10 ℃;
Inert atmosphere;
With
acetic acid;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; water;
optical yield given as %de;
diastereoselective reaction;
DOI:10.1021/jo801790r
