1-Chloro-3-(4-fluorophenyl)propan-2-one

Base Information

Chemical Name:1-Chloro-3-(4-fluorophenyl)propan-2-one
CAS No.:303967-88-6
Molecular Formula:C₉H₈ClFO
Molecular Weight:186.613
Hs Code.:
European Community (EC) Number:967-793-1
Nikkaji Number:J3.375.680A
Mol file:303967-88-6.mol

Synonyms:1-chloro-3-(4-fluorophenyl)propan-2-one;303967-88-6;2-Propanone, 1-chloro-3-(4-fluorophenyl)-;1-chloro-3-(4-fluorophenyl)acetone;3-Chloro-1-(4-fluorophenyl)propanone;SCHEMBL1151049;JFXDUAWJIMUJQN-UHFFFAOYSA-N;MFCD00041449;AKOS000174181;1-chloro-3-(4-fluoro-phenyl)-propan-2-one;EN300-39939;Z316174768

Suppliers and Price of 1-Chloro-3-(4-fluorophenyl)propan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-chloro-3-(4-fluorophenyl)propan-2-one
100mg
$ 330.00

Total 3 raw suppliers

Chemical Property of 1-Chloro-3-(4-fluorophenyl)propan-2-one

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:186.0247707
Heavy Atom Count:12
Complexity:153

Purity/Quality:

95% ^*data from raw suppliers

1-chloro-3-(4-fluorophenyl)propan-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(=O)CCl)F

Technology Process of 1-Chloro-3-(4-fluorophenyl)propan-2-one

There total 4 articles about 1-Chloro-3-(4-fluorophenyl)propan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 67442-07-3
2-chloro-N-methoxy-N-methylacetamide

: 405-50-5
p-Fluorophenylacetic acid

: 303967-88-6
1-chloro-3-(4-fluorophenyl)propan-2-one

Guidance literature:: p-Fluorophenylacetic acid; With isopropylmagnesium chloride; In tetrahydrofuran; tert-butyl methyl ether; at -10 - 25 ℃; for 1.5h; Inert atmosphere; Schlenk technique;

2-chloro-N-methoxy-N-methylacetamide; In tetrahydrofuran; tert-butyl methyl ether; at 0 - 5 ℃; for 1.25h; Inert atmosphere; Schlenk technique;
DOI:10.1021/jo5016486

Reference yield: 83.0%

: 459-03-0
4-fluorophenyl acetone

: 23211-68-9
1-chloro-1-(4-fluorophenyl)propan-2-one

: 303967-88-6
1-chloro-3-(4-fluorophenyl)propan-2-one

Guidance literature:: With [bis(acetoxy)iodo]benzene; iron(III) chloride hexahydrate; In acetic acid; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1002/adsc.201700833