Technology Process of (E)-6-styrylchromone
There total 3 articles about (E)-6-styrylchromone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); triethylamine; triphenylphosphine;
In
1-methyl-pyrrolidin-2-one;
at 100 ℃;
for 24h;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1071/CH10295
- Guidance literature:
-
Multi-step reaction with 2 steps
1: iodine / dimethyl sulfoxide / 2 h / Reflux
2: tetrakis(triphenylphosphine) palladium(0); triethylamine; triphenylphosphine / 1-methyl-pyrrolidin-2-one / 24 h / 100 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); iodine; triethylamine; triphenylphosphine;
In
1-methyl-pyrrolidin-2-one; dimethyl sulfoxide;
2: Heck reaction;
DOI:10.1071/CH10295
- Guidance literature:
-
Multi-step reaction with 5 steps
1: N-benzyl-trimethylammonium hydroxide / methanol / Heating
2: hydrogenchloride; formic acid; water / 24 h / Heating
3: polyphosphoric acid / 1 h / Heating
4: iodine / dimethyl sulfoxide / 2 h / Reflux
5: tetrakis(triphenylphosphine) palladium(0); triethylamine; triphenylphosphine / 1-methyl-pyrrolidin-2-one / 24 h / 100 °C / Inert atmosphere
With
hydrogenchloride; tetrakis(triphenylphosphine) palladium(0); formic acid; water; iodine; N-benzyl-trimethylammonium hydroxide; triethylamine; triphenylphosphine;
In
1-methyl-pyrrolidin-2-one; methanol; dimethyl sulfoxide;
1: oxa-Michael addition / 5: Heck reaction;
DOI:10.1071/CH10295
