1,1-dimethylethyl 4-{3-[(4-fluorophenyl)oxy]propanoyl}-1-piperazine carboxylate

Base Information

Chemical Name:1,1-dimethylethyl 4-{3-[(4-fluorophenyl)oxy]propanoyl}-1-piperazine carboxylate
CAS No.:1093092-10-4
Molecular Formula:C₁₈H₂₅FN₂O₄
Molecular Weight:352.406
Hs Code.:

Synonyms:1,1-dimethylethyl 4-{3-[(4-fluorophenyl)oxy]propanoyl}-1-piperazine carboxylate

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Chemical Property of 1,1-dimethylethyl 4-{3-[(4-fluorophenyl)oxy]propanoyl}-1-piperazine carboxylate

Chemical Property:

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Technology Process of 1,1-dimethylethyl 4-{3-[(4-fluorophenyl)oxy]propanoyl}-1-piperazine carboxylate

There total 1 articles about 1,1-dimethylethyl 4-{3-[(4-fluorophenyl)oxy]propanoyl}-1-piperazine carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1579-78-8
3-(4-fluoro-phenoxy)propionic acid

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 1093092-10-4
1,1-dimethylethyl 4-{3-[(4-fluorophenyl)oxy]propanoyl}-1-piperazine carboxylate

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; at 20 ℃; for 12.0333h;

Reference yield:

: 1093092-10-4
1,1-dimethylethyl 4-{3-[(4-fluorophenyl)oxy]propanoyl}-1-piperazine carboxylate

: 1-{3-[(4-fluorophenyl)oxy]propanoyl}piperazine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 2h;

Reference yield:

: 1093092-10-4
1,1-dimethylethyl 4-{3-[(4-fluorophenyl)oxy]propanoyl}-1-piperazine carboxylate

: 1093092-11-5
1-{3-[(4-fluorophenyl)oxy]propanoyl}piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C

2: sodium hydrogencarbonate / water

With hydrogenchloride; sodium hydrogencarbonate; In 1,4-dioxane; water;