2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane

Base Information

• Chemical Name: 2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane
• CAS No.: 80140-29-0
• Molecular Formula: C₃₃H₃₂O₉
• Molecular Weight: 572.612
• Mol file: 80140-29-0.mol

Synonyms:2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane

Chemical Property of 2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane

There total 8 articles about 2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-(3',4'-Dibenzyloxy)benzoyloxy-3,4,5,6-tetramethoxyacetophenone (80140-28-9) → 2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane (80140-29-0)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; Reflux;

DOI:10.1016/j.bmcl.2011.05.121

Reference yield:

2-hydroxy-3,4,5,6-tetramethoxyacetophenone (3162-28-5) + 3,4-dibenzyloxybenzoyl chloride (1486-54-0) → 2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane (80140-29-0)

Guidance literature:

With pyridine; potassium hydroxide; In hydrogenchloride; water;

Reference yield:

2-hydroxy-3,4,5,6-tetramethoxyacetophenone (3162-28-5) → 2-Hydroxy-3',4'-dibenzyloxy-3,4,5,6-tetramethoxydibenzoylmethane (80140-29-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.2 g / pyridine / 1 h / Heating

2: 1.8 g / KOH, pyridine / pyridine / 3 h

With pyridine; potassium hydroxide; In pyridine;

upstream raw materials:

2-(3',4'-Dibenzyloxy)benzoyloxy-3,4,5,6-tetramethoxyacetophenone

2-hydroxy-3,4,5,6-tetramethoxyacetophenone

3,4-dibenzyloxybenzoyl chloride

1-(2,3,4,5,6-pentamethoxyphenyl)ethan-1-one

Downstream raw materials:

3',4'-Dibenzyloxy-5,6,7,8-tetramethoxyflavone

2-(3,4-dihydroxy-phenyl)-5-hydroxy-6,7,8-trimethoxy-chromen-4-one

3',4'-dihydroxy-5,6,7,8,-tetramethoxyflavone

Acetic acid 2-(3,4-diacetoxy-phenyl)-6,7,8-trimethoxy-4-oxo-4H-chromen-5-yl ester