(2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal

Base Information

• Chemical Name: (2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal
• CAS No.: 1246760-30-4
• Molecular Formula: C₁₇H₂₀O₅
• Molecular Weight: 304.343

Synonyms:(2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal

Chemical Property of (2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal

There total 1 articles about (2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

(2R,4aS,6R,7S,8aR)-7-hydroxy-6-(hydroxymethyl)-2-(phenylsulfonylmethyl)hexahydropyrano[3,2-b]pyran-3(2H)-one benzylidene acetal (1246760-29-1) → (2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal (1246760-30-4)

Guidance literature:

(2R,4aS,6R,7S,8aR)-7-hydroxy-6-(hydroxymethyl)-2-(phenylsulfonylmethyl)hexahydropyrano[3,2-b]pyran-3(2H)-one benzylidene acetal; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In methanol; at -15 - -5 ℃;

With sodium tetrahydroborate; cerium(III) chloride heptahydrate; In methanol; at -78 - 0 ℃;

DOI:10.1016/j.tetasy.2010.04.066

Reference yield: 81.0%

(2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal (1246760-30-4) + acetic anhydride (108-24-7) → (3R,4aS,6R,7S,8aR)-7-hydroxy-6-(hydroxymethyl)-2-methyleneoctahydropyrano[3,2-b]pyran-3-yl acetate benzylidene acetal (1246760-31-5)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1016/j.tetasy.2010.04.066

Reference yield: 78.0%

(2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal (1246760-30-4) + tert-butyldimethylsilyl chloride (18162-48-6) → (2R,3S,4aR,7R,8aS)-7-(tert-butyldimethylsilyloxy)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3-ol benzylidene acetal (1246760-32-6)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.tetasy.2010.04.066

upstream raw materials:

(2R,4aS,6R,7S,8aR)-7-hydroxy-6-(hydroxymethyl)-2-(phenylsulfonylmethyl)hexahydropyrano[3,2-b]pyran-3(2H)-one benzylidene acetal

Downstream raw materials:

(3R,4aS,6R,7S,8aR)-7-hydroxy-6-(hydroxymethyl)-2-methyleneoctahydropyrano[3,2-b]pyran-3-yl acetate benzylidene acetal

(2R,3S,4aR,7R,8aS)-7-(tert-butyldimethylsilyloxy)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3-ol benzylidene acetal

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1246760-30-4 (2R,3S,4aR,7R,8aS)-2-(hydroxymethyl)-6-methyleneoctahydropyrano[3,2-b]pyran-3,7-diol benzylidene acetal

Send

Send

Metric Ton KG G Pound L ML

Send

Send