tert-Butyl (4-bromonaphthalen-1-yl)carbamate

Base Information

Chemical Name:tert-Butyl (4-bromonaphthalen-1-yl)carbamate
CAS No.:168169-11-7
Molecular Formula:C15H16BrNO2
Molecular Weight:322.19704
Hs Code.:2924299090
DSSTox Substance ID:DTXSID50937458
Wikidata:Q82913686
Mol file:168169-11-7.mol

Synonyms:168169-11-7;tert-Butyl (4-bromonaphthalen-1-yl)carbamate;1-Boc-Amino-4-bromonaphthalene;Tert-butyl N-(4-bromonaphthalen-1-yl)carbamate;tert-Butyl 4-bromonaphthalen-1-ylcarbamate;SCHEMBL593484;AMY7831;DTXSID50937458;HAJAGHHFQDXDEY-UHFFFAOYSA-N;N-Boc-4-bromo-1-aminonaphthalene;MFCD08704822;AB48600;BS-21700;CS-0371740;FT-0715267;tert-Butyl(4-bromonaphthalen-1-yl)carbamate;1-Amino-4-bromonaphthalene, N-BOC protected;F97717;EN300-7382127;TERT-BUTYL4-BROMONAPHTHALEN-1-YLCARBAMATE;A882188;(4-bromo-naphthalen-1-yl)-carbamic acid tert-butyl ester;Carbamic acid,N-(4-bromo-1-naphthalenyl)-,1,1-dimethylethyl ester;Carbamic acid, N-(4-bromo-1-naphthalenyl)-, 1,1-dimethylethyl ester

Suppliers and Price of tert-Butyl (4-bromonaphthalen-1-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Boc-Amino-4-bromonaphthalene
100mg
$ 65.00

Crysdot
tert-Butyl(4-bromonaphthalen-1-yl)carbamate 95+%
5g
$ 713.00

Chemenu
tert-Butyl(4-bromonaphthalen-1-yl)carbamate 95%
5g
$ 667.00

American Custom Chemicals Corporation
1-AMINO-4-BROMONAPHTHALENE, N-BOC PROTECTED 95.00%
1G
$ 909.56

AK Scientific
1-Boc-Amino-4-bromonaphthalene
250mg
$ 197.00

Total 16 raw suppliers

Chemical Property of tert-Butyl (4-bromonaphthalen-1-yl)carbamate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:129-133°C
Refractive Index:1.633
Boiling Point:375.867 °C at 760 mmHg
PKA:13.42±0.43(Predicted)
Flash Point:181.118 °C
PSA：38.33000
Density:1.408g/cm³
LogP:5.02230
Storage Temp.:2-8°C
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:321.03644
Heavy Atom Count:19
Complexity:327

Purity/Quality:

97% ^*data from raw suppliers

1-Boc-Amino-4-bromonaphthalene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC=C(C2=CC=CC=C21)Br

Technology Process of tert-Butyl (4-bromonaphthalen-1-yl)carbamate

There total 1 articles about tert-Butyl (4-bromonaphthalen-1-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 2298-07-9
4-Bromo-1-naphthylamine

: 168169-11-7
4-bromo-N-(tert-butoxycarbonyl)-1-naphthylamine

Guidance literature:: In ethanol; at 30 ℃; for 24h;
DOI:10.1021/acs.jmedchem.9b00632

Reference yield: 95.0%

: 168169-11-7
4-bromo-N-(tert-butoxycarbonyl)-1-naphthylamine

: 2,2-bis-(3-phenyl-prop-2-ynyl)-malonic acid dimethyl ester

: dimethyl 1-((tert-butoxycarbonyl)imino)-1',3'-diphenyl-1H,4'H-spiro[naphthalene-4,2'-pentalene]-5',5'(6'H)-dicarboxylate

Guidance literature:: With palladium diacetate; potassium carbonate; triphenylphosphine; In 1,4-dioxane; at 100 ℃; for 16h; Glovebox; Sealed tube; Inert atmosphere;
DOI:10.1002/anie.201601570

Reference yield: 83.0%

: 582-33-2
3-aminobenzoic acid ethyl ester

: 168169-11-7
4-bromo-N-(tert-butoxycarbonyl)-1-naphthylamine

: ethyl 3-(4-((tert-butoxycarbonyl)amino)-1-naphthylamino)benzoate

Guidance literature:: With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 80 ℃; for 18h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.9b00632