(Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal

Base Information

Chemical Name:(Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal
CAS No.:623926-62-5
Molecular Formula:C₂₇H₄₄O₄Si
Molecular Weight:460.729
Hs Code.:

Synonyms:(Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal

Suppliers and Price of (Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal

There total 6 articles about (Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 623926-61-4
(4R,5R,6S,7S,Z)-6-(4-methoxybenzyloxy)-4-(tert-butyldimethylsilyloxy)-5,7-dimethylundeca-8,10-dien-1-ol

: 623926-62-5
(Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 0 - 20 ℃;
DOI:10.1016/S0968-0896(03)00186-X

Reference yield:

: 106296-58-6
(2S,3S,4S)-(1-tert-butyldimethylsilanyloxy)-2,4-dimethylhex-5-en-3-ol

: 623926-62-5
(Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal

Guidance literature:: Multi-step reaction with 10 steps

1.1: 95 percent / Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

2.1: 95 percent / HF-pyridine; pyridine / tetrahydrofuran / 12 h / 20 °C

3.1: Dess-Martin periodinane / CH₂Cl₂ / 0 - 20 °C

4.1: Mg; 1,2-dibromoethane / tetrahydrofuran / 1 h / 20 °C

4.2: 1.83 g / tetrahydrofuran / 10 h / 20 °C

5.1: 91 percent / NaH; TBAI / tetrahydrofuran

6.1: ozone; pyridine / methanol; CH₂Cl₂ / -78 °C

6.2: dimethyl sulfide / methanol; CH₂Cl₂

7.1: CrCl₂ / tetrahydrofuran / 16 h / 20 °C

8.1: NaH / tetrahydrofuran / 0 - 20 °C

9.1: 83 percent / HF-pyridine; pyridine / tetrahydrofuran / 12 h / 20 °C

10.1: 100 percent / Dess-Martin periodinane / CH₂Cl₂ / 0 - 20 °C

With pyridine; chromium dichloride; tetra-(n-butyl)ammonium iodide; sodium hydride; Dess-Martin periodane; pyridine hydrogenfluoride; ozone; magnesium; ethylene dibromide; triethylamine; In tetrahydrofuran; methanol; dichloromethane; 3.1: Dess-Martin oxidation / 4.2: Grignard reaction / 7.1: Nozaki-Hiyama reaction / 10.1: Dess-Martin oxidation;
DOI:10.1016/S0968-0896(03)00186-X

Reference yield:

: 623926-31-8
(4R,5S,6S,7S)-1,6-bis(tert-butyldimethylsilanyloxy)-5,7-dimethylnon-8-en-4-ol

: 623926-62-5
(Z)-(4R,5R,6S,7S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-5,7-dimethyl-undeca-8,10-dienal

Guidance literature:: Multi-step reaction with 6 steps

1.1: 91 percent / NaH; TBAI / tetrahydrofuran

2.1: ozone; pyridine / methanol; CH₂Cl₂ / -78 °C

2.2: dimethyl sulfide / methanol; CH₂Cl₂

3.1: CrCl₂ / tetrahydrofuran / 16 h / 20 °C

4.1: NaH / tetrahydrofuran / 0 - 20 °C

5.1: 83 percent / HF-pyridine; pyridine / tetrahydrofuran / 12 h / 20 °C

6.1: 100 percent / Dess-Martin periodinane / CH₂Cl₂ / 0 - 20 °C

With pyridine; chromium dichloride; tetra-(n-butyl)ammonium iodide; sodium hydride; Dess-Martin periodane; pyridine hydrogenfluoride; ozone; In tetrahydrofuran; methanol; dichloromethane; 3.1: Nozaki-Hiyama reaction / 6.1: Dess-Martin oxidation;
DOI:10.1016/S0968-0896(03)00186-X