623926-61-4

Upstream product

• 623926-59-0 1-[(1S,2R,3R)-3,6-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methyl-1-((S)-1-methyl-allyl)-hexyloxymethyl]-4-methoxy-benzene 
• 106296-58-6 (2S,3S,4S)-(1-tert-butyldimethylsilanyloxy)-2,4-dimethylhex-5-en-3-ol 
• 1026307-82-3 (2R,3R,4R,5R)-5,8-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-octanal 
• 252342-49-7 (2R,3S,4S)-3-hydroxy-5-(4-methoxybenzyloxy)-2,4-dimethylpentanoic acid methoxymethylamide 
• 945402-42-6 C₂₄H₄₄O₅Si 
• 945402-11-9 (2S,3S,4R,5R)-3-(4-methoxybenzyloxy)-5,8-bis(tert-butyldimethylsilyloxy)-2,4-dimethyloctan-1-ol 
• 945402-10-8 (2S,4S,5S)-4-((2R,3R)-3,6-bis(tert-butyldimethylsilyloxy)hexan-2-yl)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxane 
• 945402-09-5 (2S,3S,4S,5R)-1-(4-methoxybenzyloxy)-8-(tert-butyldimethylsilyloxy)-2,4-dimethyloctane-3,5-diol 
• 945402-33-5 (5R,6S,7S)-8-(4-methoxybenzyloxy)-1-(tert-butyldimethylsilyloxy)-6-hydroxy-5,7-dimethyloctan-4-one 
• 623926-60-3 1-(((5S,6S,7R,8R,Z)-8,11-bis(tert-butyldimethylsilyloxy)-5,7-dimethylundeca-1,3-dien-6-yloxy)methyl)-4-methoxybenzene 

Downstream Products

• 945402-35-7 ((4R,5R,6S,7S,Z)-6-(4-methoxybenzyloxy)-1-iodo-5,7-dimethylundeca-8,10-dien-4-yloxy)(tert-butyl)dimethylsilane 
• 945402-12-0 1-(((3Z,5S,6S,7R,8R,11Z,13S,14R,15S,16Z)-8,14-bis(tert-butyldimethylsilyloxy)-17-iodo-5,7,13,15-tetramethylheptadeca-1,3,11,16-tetraen-6-yloxy)methyl)-4-methoxybenzene 
• 945402-13-1 (2Z,4E,6R,7S,9S,10Z,12S,13R,14S,15Z,19R,20R,21S,22S,23Z)-21-(4-methoxybenzyloxy)-1,7,13,19-tetrakis(tert-butyldimethylsilyloxy)-6,12,14,20,22-pentamethylhexacosa-2,4,10,15,23,25-hexaen-9-ol 
• 945402-21-1 (2Z,4E,6R,7S,9R,10Z,12S,13R,14S,15Z,19R,20R,21S,22S,23Z)-21-(4-methoxybenzyloxy)-1,7,13,19-tetrakis(tert-butyldimethylsilyloxy)-6,12,14,20,22-pentamethylhexacosa-2,4,10,15,23,25-hexaen-9-ol 
• 945402-14-2 (2Z,4E,6R,7S,9S,10Z,12S,13R,14S,15Z,19R,20R,21S,22S,23Z)-21-(4-methoxybenzyloxy)-7,9,13,19-tetrakis(tert-butyldimethylsilyloxy)-6,12,14,20,22-pentamethylhexacosa-2,4,10,15,23,25-hexaen-9-ol 
• 945402-36-8 C₆₉H₁₃₀O₇Si₅ 
• 945402-38-0 (2Z,4E,6R,7S,9S,10Z,12S,13R,14S,15Z,19R,20R,21S,22S,23Z)-21-(4-methoxybenzyloxy)-7,9,13,19-tetrakis(tert-butyldimethylsilyloxy)-6,12,14,20,22-pentamethylhexacosa-2,4,10,15,23,25-hexaenoic acid 
• 945402-37-9 C₆₃H₁₁₄O₇Si₄ 
• 945403-12-3 (2Z,4E,6R,7S,9R,10Z,12S,13R,14S,15Z,19R,20R,21S,22S,23Z)-21-(4-methoxybenzyloxy)-7,9,13,19-tetrakis(tert-butyldimethylsilyloxy)-6,12,14,20,22-pentamethylhexacosa-2,4,10,15,23,25-hexaen-9-ol 
• 945402-41-5 C₆₉H₁₃₀O₇Si₅ 
• 945402-39-1 C₆₃H₁₁₄O₇Si₄ 
• 945402-40-4 C₆₃H₁₁₄O₈Si₄ 
• 623926-75-0 (5Z,13Z)-(2S,3S,4S,9R,10R,11S,12S)-9-(tert-Butyl-dimethyl-silanyloxy)-3,11-bis-(4-methoxy-benzyloxy)-2,4,10,12-tetramethyl-hexadeca-5,13,15-trien-1-ol 
• 623926-82-9 Acetic acid (4Z,9Z)-(1R,6S,7R,8S)-13-hydroxy-7-(4-methoxy-benzyloxy)-1-[(Z)-(1S,2S,3S)-2-(4-methoxy-benzyloxy)-1,3-dimethyl-hepta-4,6-dienyl]-6,8-dimethyl-trideca-4,9-dienyl ester 

Relevant academic research and scientific papers

Total synthesis and biological evaluation of C16 analogs of (-)-dictyostatin

The structure-activity relationship of the crucial C16 region of (-)-dictyostatin was established through total synthesis of analogs followed by detailed biological characterization. A versatile synthetic strategy was used to prepare milligram quantities

Synthesis and biological assessment of simplified analogues of the potent microtubule stabilizer (+)-discodermolide

An efficient, convergent and stereocontrolled synthesis of simplified analogues of the potent antimitotic agent (+)-discodermolide has been achieved and several small libraries have been prepared. In all the libraries, the discodermolide methyl groups at