2,4-Dichloro-6-methylbenzylamine

Base Information

• Chemical Name: 2,4-Dichloro-6-methylbenzylamine
• CAS No.: 150517-76-3
• Molecular Formula: C8H9Cl2N
• Molecular Weight: 190.072
• Hs Code.: 2921499090
• DSSTox Substance ID: DTXSID10384202
• Wikidata: Q82176173
• Mol file: 150517-76-3.mol

Synonyms:2,4-dichloro-6-methylbenzylamine;150517-76-3;(2,4-dichloro-6-methylphenyl)methanamine;Benzenemethanamine, 2,4-dichloro-6-methyl-;(2,4-dichloro-6-methylbenzyl)amine hydrochloride;4,6-Dichloro-2-methylbenzylamine;MFCD00052913;Benzenemethanamine,2,4-dichloro-6-methyl-;SCHEMBL110348;DTXSID10384202;QISTWSMZJRTDCS-UHFFFAOYSA-N;AKOS006228760;AS-65626;BP-13186;AM20030024;CS-0318503;FT-0610027;C80052;A846810;1-(2,4-DICHLORO-6-METHYLPHENYL)METHANAMINE

Chemical Property of 2,4-Dichloro-6-methylbenzylamine

Chemical Property:

• Vapor Pressure: 0.00421mmHg at 25°C
• Melting Point: 47 °C
• Refractive Index: 1.573
• Boiling Point: 278.6 °C at 760 mmHg
• PKA: 8.49±0.10(Predicted)
• Flash Point: 122.3 °C
• PSA: 26.02000
• Density: 1.27 g/cm³
• LogP: 3.46080
• Sensitive.: Air Sensitive
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 189.0112047
• Heavy Atom Count: 11
• Complexity: 129

Purity/Quality:

98%Min ^*data from raw suppliers

2,4-Dichloro-6-methylbenzylamine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R34:Causes burns.
• Hazard Codes: C:Corrosive
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1CN)Cl)Cl

Technology Process of 2,4-Dichloro-6-methylbenzylamine

There total 1 articles about 2,4-Dichloro-6-methylbenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2,4-dichloro-6-methylbenzylamine (150517-76-3)

Guidance literature:

Reference yield: 92.0%

2,4-dichloro-6-methylbenzylamine (150517-76-3) + 3-ethoxy-4-(1,1-dimethyl-propylamino)-cyclobut-3-ene-1,2-dione (202521-88-8) → WAY-151616 (202520-55-6)

Guidance literature:

In ethanol; at 20 ℃; for 72h;

DOI:10.1021/jm9905108

Reference yield: 89.0%

3-(1,1-dimethylethylamino)-4-ethoxy-3-cyclobutene-1,2-dione (186184-26-9) + 2,4-dichloro-6-methylbenzylamine (150517-76-3) → 3-tert-butylamino-4-(2,4-dichloro-6-methyl-benzylamino)-cyclobut-3-ene-1,2-dione

Guidance literature:

In ethanol; at 20 ℃; for 72h;

DOI:10.1021/jm9905108

Downstream raw materials:

WAY-151616

2,4-dichloro-6-methyl-benzylamine hydrochloride

C₂₃H₂₈Cl₂N₂O₃S

(R)-2,3-dihydro-furo[2,3-b]pyridine-3-carboxylic acid 2,4-dichloro-6-methyl-benzylamide

Refernces