N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

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Chemical Name:N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine
CAS No.:1004544-49-3
Molecular Formula:C₂₈H₃₇N₃
Molecular Weight:415.622
Hs Code.:

Synonyms:N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

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Chemical Property of N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

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Technology Process of N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

There total 3 articles about N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1004546-88-6
(+/-)-2-(4-(dimethylamino)-4-phenylcyclohex-1-enyl)-3-(2-(pyrrolidin-1-yl)ethyl)-1H-indole

: 1004544-51-7
N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

: 1004544-49-3
N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

Guidance literature:: (+/-)-2-(4-(dimethylamino)-4-phenylcyclohex-1-enyl)-3-(2-(pyrrolidin-1-yl)ethyl)-1H-indole; With tin; hydrogen bromide; In acetic acid; at 20 ℃; for 4.5h;

With sodium hydroxide; In dichloromethane;

Reference yield:

: 65619-20-7
4-dimethylamino-4-phenylcyclohexanone

: 1004544-49-3
N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 24 h / 20 °C

1.2: 0.33 h

2.1: tin; hydrogen bromide / acetic acid / 4.5 h / 20 °C

With tin; trifluorormethanesulfonic acid; hydrogen bromide; In dichloromethane; acetic acid;

Reference yield:

: 14008-96-9
3-(2-(pyrrolidin-1-yl)ethyl)-1H-indole

: 1004544-51-7
N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

: 1004544-49-3
N,N-dimethyl-1-phenyl-4-(3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-2-yl)cyclohexanamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 24 h / 20 °C

1.2: 0.33 h

2.1: tin; hydrogen bromide / acetic acid / 4.5 h / 20 °C

With tin; trifluorormethanesulfonic acid; hydrogen bromide; In dichloromethane; acetic acid;