65619-20-7

Basic information

• Product Name: 4-(dimethylamino)-4-phenylcyclohexan-1-one
• Synonyms: 4-(dimethylamino)-4-phenylcyclohexan-1-one;4-(Dimethylamino)-4-phenylcyclohexanone
• CAS NO: 65619-20-7
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.30676
• Mol File: 65619-20-7.mol
• Article Data: 18

Chemical Properties

• Melting Point: 98-99.5 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 333.5±42.0 °C(Predicted)
• Appearance: /
• Density: 1.05±0.1 g/cm3(Predicted)
• PKA: 8.15±0.20(Predicted)
• CAS DataBase Reference: 4-(dimethylamino)-4-phenylcyclohexan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(dimethylamino)-4-phenylcyclohexan-1-one(65619-20-7)
• EPA Substance Registry System: 4-(dimethylamino)-4-phenylcyclohexan-1-one(65619-20-7)

Safety Data

• Hazardous Substances Data: 65619-20-7(Hazardous Substances Data)

Usage

General Description

4-(dimethylamino)-4-phenylcyclohexan-1-one is a chemical compound with the molecular formula C15H19NO. It is a ketone derivative with a cyclohexane ring substituted with a phenyl group and a dimethylamino group. 4-(dimethylamino)-4-phenylcyclohexan-1-one is commonly used as a precursor in the synthesis of various pharmaceuticals and organic compounds. It may also have some potential applications in medicinal and chemical research. However, it is important to handle this compound with care as it may have potential health hazards if not properly managed.

Upstream product

• 77253-85-1 dimethyl-(8-phenyl-1,4-dioxaspiro[4.5]decan-8-yl)amine 
• 100-58-3 phenylmagnesium bromide 
• 1071066-97-1 N-(1,4-dioxaspiro-[4,5]-decan-8-yliden)-methanamine 
• 79741-33-6 methyl-(8-phenyl-1,4-dioxaspiro[4.5]dec-8-yl)amine 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 65618-70-4 4-(p-chlorophenyl)-4-dimethylaminocyclohexanone, ethylene ketal hydrochloride 
• 100-59-4 phenylmagnesium chloride 
• 65619-92-3 8-(dimethylamino)-1,4-dioxaspiro-[4.5]-decane-8-carbonitrile 
• 65619-18-3 4-methylamino-4-phenylcyclohexanone, ethylene ketal hydrochloride 
• 591-51-5 phenyllithium 
• 65619-19-4 4-dimethylamino-4-phenylcyclohexanone, ethylene ketal hydrochloride 

Downstream Products

• 76825-04-2 cis-4-Dimethylamino-4-phenylcyclohexanol 
• 76825-05-3 trans-4-Dimethylamino-4-phenylcyclohexanol 
• 1002915-80-1 4-(dimethylamino)-4-phenyl-spiro[cyclohexane-1,8'-(5,6,8,9-tetrahydropyrano[3,4-b]-7-azaindole)] 
• 1002916-23-5 4-(dimethylamino)-4-phenyl-spiro[cyclohexane-1,8'-(3-trifluoromethyl-5,6,8,9-tetrahydropyrano[3,4-b]-7-azaindole)] 
• 1002916-29-1 4-(dimethylamino)-4-phenyl-spiro[cyclohexane-1,8'-(5,6,8,9-tetrahydro-thiopyrano[3,4-b]-7-azaindole)] 
• 1002916-31-5 4-(dimethylamino)-4-phenyl-spiro[cyclohexane-1,6'-(5,6,8,9-tetrahydro-thiopyrano[3,4-b]-5-azaindole)] 
• 1002916-15-5 C₂₃H₂₇N₃O 
• 1002916-13-3 C₂₃H₂₇N₃O 
• 1189752-75-7 N,N-dimethyl-4,4-bis(3-methylbenzofuran-2-yl)-1-phenylcyclohexanamine 
• 1189795-75-2 4-dimethylamino-4-phenyl-1-(pyrrolidin-1-yl)cyclohexane carbonitrile 
• 1189795-74-1 1,4-bis-dimethylamino-4-phenyl-cyclohexane carbonitrile 
• 1189795-76-3 4-dimethylamino-1-methylamino-4-phenyl-cyclohexane carbonitrile 
• 1189795-77-4 [4-methoxy-4-(3-methoxy-prop-1-ynyl)-1-phenyl-cyclohexyl]-dimethylamine 
• 1189795-80-9 N,N-dimethyl-4-methylene-1-phenylcyclohexan-1-amine 

Relevant articles and documents

4,5-DIHYDRO-1H-THIENO[2,3-G]INDAZOLYL DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

wherein the meanings for the various substituents are as disclosed in the description, having dual pharmacological activity towards both the α2δ subunit, in particular the α2δ-1 subunit, of the voltage-gated calcium channel and the μ-opioid receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.

3-((HETERO-)ARYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES

The invention relates to 3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.

3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives

The invention relates to 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.