(E)-3-styrylbiphenyl

Base Information

• Chemical Name: (E)-3-styrylbiphenyl
• CAS No.: 52500-13-7
• Molecular Formula: C₂₀H₁₆
• Molecular Weight: 256.347
• Mol file: 52500-13-7.mol

Synonyms:(E)-3-styrylbiphenyl

Chemical Property of (E)-3-styrylbiphenyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-styrylbiphenyl

There total 11 articles about (E)-3-styrylbiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C15H11F3O3S + phenylboronic acid (98-80-6) → (E)-3-styrylbiphenyl (52500-13-7)

Guidance literature:

With Pd-catalyst;

DOI:10.1021/acscatal.6b00675

Reference yield:

2-phenyl-6-[(E)-styryl]benzoic acid → (E)-3-styrylbiphenyl (52500-13-7)

Guidance literature:

With silver(I) acetate; potassium carbonate; In N,N-dimethyl acetamide; at 160 ℃; for 4h; Inert atmosphere;

DOI:10.1021/ol1027392

Reference yield:

2-cyanophenyl ethyl benzylphosphonate → (E)-3-styrylbiphenyl (52500-13-7)

Guidance literature:

Multi-step reaction with 4 steps

1: palladium diacetate; L-N-Boc-Ala; benzene / 24 h / 80 °C

2: potassium tert-butylate / toluene / 70 °C

3: potassium phosphate / toluene; water

4: Pd-catalyst

With potassium phosphate; L-N-Boc-Ala; benzene; potassium tert-butylate; palladium diacetate; In water; toluene; 2: |Horner-Wadsworth-Emmons Olefination;

DOI:10.1021/acscatal.6b00675

upstream raw materials:

styrene

2-Biphenylcarboxylic acid

1-bromo-3-chlorobenzene

(E)-3-chlorostilbene

Downstream raw materials:

1-(m-biphenylyl)-2-phenylethyne

Refernces

• 1、 Cotugno, Pietro,Monopoli, Antonio,Ciminale, Francesco,Cioffi, Nicola,Nacci, Angelo. "Pd nanoparticle catalysed one-pot sequential Heck and Suzuki couplings of bromo-chloroarenes in ionic liquids and water". . p. 808 - 813. Retrieved 2012/02/05.
• 2、 Mochida, Satoshi,Hirano, Koji,Satoh, Tetsuya,Miura, Masahiro. "Synthesis of stilbene and distyrylbenzene derivatives through rhodium-catalyzed ortho -olefination and decarboxylation of benzoic acids". . p. 5776 - 5779. Retrieved 2011/03/18.