2-Pyridinemethanol, alpha-methyl-6-phenyl-, 2-acetate, (alphaR)-

Base Information

Chemical Name:2-Pyridinemethanol, alpha-methyl-6-phenyl-, 2-acetate, (alphaR)-
CAS No.:204244-63-3
Molecular Formula:C₁₅H₁₅NO₂
Molecular Weight:241.29
Hs Code.:
DSSTox Substance ID:DTXSID401199092

Synonyms:DTXSID401199092;2-Pyridinemethanol, alpha-methyl-6-phenyl-, 2-acetate, (alphaR)-;204244-63-3

Suppliers and Price of 2-Pyridinemethanol, alpha-methyl-6-phenyl-, 2-acetate, (alphaR)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-Pyridinemethanol, alpha-methyl-6-phenyl-, 2-acetate, (alphaR)-

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:241.110278721
Heavy Atom Count:18
Complexity:274

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC=CC(=N1)C2=CC=CC=C2)OC(=O)C
Isomeric SMILES:C[C@H](C1=CC=CC(=N1)C2=CC=CC=C2)OC(=O)C

Technology Process of 2-Pyridinemethanol, alpha-methyl-6-phenyl-, 2-acetate, (alphaR)-

There total 3 articles about 2-Pyridinemethanol, alpha-methyl-6-phenyl-, 2-acetate, (alphaR)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 876-27-7
4-chlorophenyl acetate

: 139163-61-4
α-methyl-6-phenyl-2-pyridinemethanol

: 204244-63-3
(R)-2-(1-acetoxyethyl)-6-phenylpyridine

Guidance literature:: With Candida antarctica lipase B; 1-hydroxytetraphenylcyclopentadienyl(tetraphenyl-2,4-cyclopentadien-1-one)-μ-hydrotetracarbonyldiruthenium(II); In toluene; at 70 ℃; for 46h; optical yield given as %ee; Inert atmosphere; Enzymatic reaction;
DOI:10.1021/jo900271x

Reference yield: 45.0%

: 108-05-4,9003-20-7
vinyl acetate

: 139163-61-4
α-methyl-6-phenyl-2-pyridinemethanol

: 138983-03-6
(R)-2-(1-hydroxyethyl)-6-phenylpyridine

: 162238-28-0
(S)-2-(1-hydroxyethyl)-6-phenylpyridine

: 204244-63-3
(R)-2-(1-acetoxyethyl)-6-phenylpyridine

Guidance literature:: With Candida antarctica lipase B; In tert-butyl methyl ether; at 20 ℃; optical yield given as %ee; Resolution of racemate; Inert atmosphere; Enzymatic reaction;
DOI:10.1021/jo900271x

Reference yield: 45.0%

: 108-05-4,9003-20-7
vinyl acetate

: 139163-61-4
α-methyl-6-phenyl-2-pyridinemethanol

: 162238-28-0
(S)-2-(1-hydroxyethyl)-6-phenylpyridine

: 204244-63-3
(R)-2-(1-acetoxyethyl)-6-phenylpyridine

Guidance literature:: With 4 A molecular sieve; In di-isopropyl ether; for 7h; Ambient temperature; Candida antarctica lipase presence;
DOI:10.1021/jo971521g