N-[1-[4'-[(difluoromethyl)thio] [1,1'-biphenyl]-4-yl]-2-hydroxyethyl]-2,6-difluorobenzamide

Base Information

Chemical Name:N-[1-[4'-[(difluoromethyl)thio] [1,1'-biphenyl]-4-yl]-2-hydroxyethyl]-2,6-difluorobenzamide
CAS No.:207974-61-6
Molecular Formula:C₂₂H₁₇F₄NO₂S
Molecular Weight:435.442
Hs Code.:

Synonyms:N-[1-[4'-[(difluoromethyl)thio] [1,1'-biphenyl]-4-yl]-2-hydroxyethyl]-2,6-difluorobenzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[1-[4'-[(difluoromethyl)thio] [1,1'-biphenyl]-4-yl]-2-hydroxyethyl]-2,6-difluorobenzamide

Chemical Property:

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Technology Process of N-[1-[4'-[(difluoromethyl)thio] [1,1'-biphenyl]-4-yl]-2-hydroxyethyl]-2,6-difluorobenzamide

There total 1 articles about N-[1-[4'-[(difluoromethyl)thio] [1,1'-biphenyl]-4-yl]-2-hydroxyethyl]-2,6-difluorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 207974-86-5
β-amino-4'-[(difluoromethyl)thio][1,1'-biphenyl]-4-ethanol hydrochloride salt

: 18063-02-0
2,6-difluorobenzoylchloride

: 207974-61-6
N-[1-[4'-[(difluoromethyl)thio] [1,1'-biphenyl]-4-yl]-2-hydroxyethyl]-2,6-difluorobenzamide

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; water;

Reference yield:

: 207974-61-6
N-[1-[4'-[(difluoromethyl)thio] [1,1'-biphenyl]-4-yl]-2-hydroxyethyl]-2,6-difluorobenzamide

: 207974-62-7
N-[2-chloro-1-[4'-[(difluoromethyl)thio][1,1'-biphenyl]-4-yl]ethyl]-2,6-difluorobenzamide

Guidance literature:: With thionyl chloride; In toluene;

Reference yield:

: 207974-61-6
N-[1-[4'-[(difluoromethyl)thio] [1,1'-biphenyl]-4-yl]-2-hydroxyethyl]-2,6-difluorobenzamide

: 4-[4'-[(difluoromethyl)thio][1,1'-biphenyl]-4-yl]-2-(2,6-difluorophenyl)-4,5-dihydrooxazole

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / toluene

2: sodium hydroxide / N,N-dimethyl-formamide

With sodium hydroxide; thionyl chloride; In N,N-dimethyl-formamide; toluene;