3-chloro-2-(4-chloro-2-fluoro-5-methyl-phenyl)-5-trifluoromethyl-pyridine

Base Information

Chemical Name:3-chloro-2-(4-chloro-2-fluoro-5-methyl-phenyl)-5-trifluoromethyl-pyridine
CAS No.:699011-24-0
Molecular Formula:C₁₃H₇Cl₂F₄N
Molecular Weight:324.105
Hs Code.:

Synonyms:3-chloro-2-(4-chloro-2-fluoro-5-methyl-phenyl)-5-trifluoromethyl-pyridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-chloro-2-(4-chloro-2-fluoro-5-methyl-phenyl)-5-trifluoromethyl-pyridine

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Technology Process of 3-chloro-2-(4-chloro-2-fluoro-5-methyl-phenyl)-5-trifluoromethyl-pyridine

There total 1 articles about 3-chloro-2-(4-chloro-2-fluoro-5-methyl-phenyl)-5-trifluoromethyl-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 69045-84-7
2,3-dichloro-5-trifluoromethylpyridine

: 325786-09-2
4-chloro-2-fluoro-5-methylphenylboronic acid

: 699011-24-0
3-chloro-2-(4-chloro-2-fluoro-5-methyl-phenyl)-5-trifluoromethyl-pyridine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate;
DOI:10.2533/000942903777678650

Reference yield: 95.0%

: 699011-24-0
3-chloro-2-(4-chloro-2-fluoro-5-methyl-phenyl)-5-trifluoromethyl-pyridine

: 699011-25-1
3-chloro-2-(4-chloro-5-dibromomethyl-2-fluoro-phenyl)-5-trifluoromethyl-pyridine

Guidance literature:: With N-Bromosuccinimide; In tetrachloromethane; Irradiation;
DOI:10.2533/000942903777678650

Reference yield:

: 699011-24-0
3-chloro-2-(4-chloro-2-fluoro-5-methyl-phenyl)-5-trifluoromethyl-pyridine

: 195304-20-2
2-chloro-5-(3-chloro-5-trifluoromethylpyrid-2-yl)-4-fluorobenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / NBS / CCl₄ / Irradiation

2: 74 percent / H₂SO₄

With N-Bromosuccinimide; sulfuric acid; In tetrachloromethane;
DOI:10.2533/000942903777678650